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STAT3 Oligonucleotide Inhibits Tumor Angiogenesis in Preclinical Models of Squamous Cell Carcinoma
PURPOSE: Signal transducer and activator of transcription 3 (STAT3) has shown to play a critical role in head and neck squamous cell carcinoma (HNSCC) and we have recently completed clinical trials of STAT3 decoy oligonucleotide in patients with recurrent or metastatic HNSCC. However, there is limit...
Autores principales: | Klein, Jonah D., Sano, Daisuke, Sen, Malabika, Myers, Jeffrey N., Grandis, Jennifer R., Kim, Seungwon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880270/ https://www.ncbi.nlm.nih.gov/pubmed/24404126 http://dx.doi.org/10.1371/journal.pone.0081819 |
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