HRES-1/Rab4 Promotes the Formation of LC3(+) Autophagosomes and the Accumulation of Mitochondria during Autophagy

HRES-1/Rab4 is a small GTPase that regulates endocytic recycling. It has been colocalized to mitochondria and the mechanistic target of rapamycin (mTOR), a suppressor of autophagy. Since the autophagosomal membrane component microtubule-associated protein light chain 3 (LC3) is derived from mitochon...

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Detalles Bibliográficos
Autores principales: Talaber, Gergely, Miklossy, Gabriella, Oaks, Zachary, Liu, Yuxin, Tooze, Sharon A., Chudakov, Dmitriy M., Banki, Katalin, Perl, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880286/
https://www.ncbi.nlm.nih.gov/pubmed/24404161
http://dx.doi.org/10.1371/journal.pone.0084392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880286/
https://www.ncbi.nlm.nih.gov/pubmed/24404161
http://dx.doi.org/10.1371/journal.pone.0084392

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