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T Cells Detect Intracellular DNA but Fail to Induce Type I IFN Responses: Implications for Restriction of HIV Replication
HIV infects key cell types of the immune system, most notably macrophages and CD4+ T cells. Whereas macrophages represent an important viral reservoir, activated CD4+ T cells are the most permissive cell types supporting high levels of viral replication. In recent years, it has been appreciated that...
Autores principales: | Berg, Randi K., Rahbek, Stine H., Kofod-Olsen, Emil, Holm, Christian K., Melchjorsen, Jesper, Jensen, David G., Hansen, Anne Louise, Jørgensen, Louise B., Ostergaard, Lars, Tolstrup, Martin, Larsen, Carsten S., Paludan, Søren R., Jakobsen, Martin R., Mogensen, Trine H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880311/ https://www.ncbi.nlm.nih.gov/pubmed/24404168 http://dx.doi.org/10.1371/journal.pone.0084513 |
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