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Exploring Physical and Chemical Factors Influencing the Properties of Recombinant Prion Protein and the Real-Time Quaking-Induced Conversion (RT-QuIC) Assay

Real-time quaking-induced conversion (RT-QuIC), a highly specific and sensitive assay able to detect low levels of the disease-inducing isoform of the prion protein (PrP(d)) in brain tissue biopsies and cerebral spinal fluid, has great potential to become a method for diagnosing prion disease ante m...

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Detalles Bibliográficos
Autores principales:	Cheng, Keding, Sloan, Angela, Avery, Kristen M., Coulthart, Michael, Carpenter, Michael, Knox, J. David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880330/ https://www.ncbi.nlm.nih.gov/pubmed/24404191 http://dx.doi.org/10.1371/journal.pone.0084812

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