The mononuclear metal center of type-I dihydroorotase from aquifex aeolicus

BACKGROUND: Dihydroorotase (DHO) is a zinc metalloenzyme, although the number of active site zinc ions has been controversial. E. coli DHO was initially thought to have a mononuclear metal center, but the subsequent X-ray structure clearly showed two zinc ions, α and β, at the catalytic site. Aquife...

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Detalles Bibliográficos
Autores principales: Edwards, Brian FP, Fernando, Roshini, Martin, Philip D, Grimley, Edward, Cordes, Melissa, Vaishnav, Asmita, Brunzelle, Joseph S, Evans, Hedeel Guy, Evans, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880350/
https://www.ncbi.nlm.nih.gov/pubmed/24314009
http://dx.doi.org/10.1186/1471-2091-14-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880350/
https://www.ncbi.nlm.nih.gov/pubmed/24314009
http://dx.doi.org/10.1186/1471-2091-14-36

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