Essential role of axonal VGSC inactivation in time-dependent deceleration and unreliability of spike propagation at cerebellar Purkinje cells

BACKGROUND: The output of the neuronal digital spikes is fulfilled by axonal propagation and synaptic transmission to influence postsynaptic cells. Similar to synaptic transmission, spike propagation on the axon is not secure, especially in cerebellar Purkinje cells whose spiking rate is high. The c...

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Detalles Bibliográficos
Autores principales: Yang, Zhilai, Gu, Erwei, Lu, Xianfu, Wang, Jin-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880351/
https://www.ncbi.nlm.nih.gov/pubmed/24382121
http://dx.doi.org/10.1186/1756-6606-7-1

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