Cargando…

BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor beta [TGF-β1] in colorectal tumour cells

As colorectal cancer remains the second highest cause of cancer-related deaths in much of the industrialised world, identifying novel strategies to prevent colorectal tumour development remains an important challenge. BAG-1 is a multi-functional protein, the expression of which is up-regulated at re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Skeen, Victoria R., Collard, Tracey J., Southern, Samantha L., Greenhough, Alexander, Hague, Angela, Townsend, Paul, Paraskeva, Christos, Williams, Ann C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880928/ https://www.ncbi.nlm.nih.gov/pubmed/23108401 http://dx.doi.org/10.1038/onc.2012.480

Ejemplares similares

BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis
por: Southern, Samantha L., et al.
Publicado: (2011)

The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cells
por: Collard, T J, et al.
Publicado: (2012)

Regulation of osteoblast development by Bcl-2-associated athanogene-1 (BAG-1)
por: Greenhough, Joanna, et al.
Publicado: (2016)

BAG-1 expression and function in human cancer
por: Cutress, R I, et al.
Publicado: (2002)

BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells
por: Legge, Danny N., et al.
Publicado: (2019)

BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling
por: Urban, Bettina C, et al.
Publicado: (2016)

Transforming growth factor beta 1 (TGF-beta 1) produced in tumour tissue after chemotherapy acts as a lymphokine-activated killer attractant.
por: Kuramitsu, Y., et al.
Publicado: (1996)

Expression of transforming growth factor beta (TGF beta) receptors and expression of TGF beta 1, TGF beta 2 and TGF beta 3 in human small cell lung cancer cell lines.
por: Damstrup, L., et al.
Publicado: (1993)

Immunoregulatory role of transforming growth factor beta (TGF-beta) in development of killer cells: comparison of active and latent TGF-beta 1
Publicado: (1990)

Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: implications for TGF-beta-driven synovial inflammation and hyperplasia
Publicado: (1991)

Elevated plasma levels of transforming growth factor (TGF)-beta1 and TGF-beta2 in patients with disseminated malignant melanoma.
por: Krasagakis, K., et al.
Publicado: (1998)

Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells
por: Morgan, R G, et al.
Publicado: (2015)

Co-overexpression of Bag-1 and heat shock protein 70 in human epidermal squamous cell carcinoma: Bag-1-mediated resistance to 5-fluorouracil-induced apoptosis
por: Wood, J, et al.
Publicado: (2011)

Transforming growth factor beta1 (TGF-beta1) is a preoperative prognostic indicator in advanced gastric carcinoma.
por: Nakamura, M., et al.
Publicado: (1998)

Cell-cell contact and specific cytokines inhibit apoptosis of colonic epithelial cells: growth factors protect against c-myc-independent apoptosis.
por: Hague, A., et al.
Publicado: (1997)

Transforming growth factor beta 1, a cytokine with regenerative functions
por: Sulaiman, Wale, et al.
Publicado: (2016)

Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia
Publicado: (1990)

Age-Dependent Decrease in Serum Transforming Growth Factor (TGF)-Beta 1 in Healthy Japanese Individuals; Population Study of Serum TGF-Beta 1 Level in Japanese
por: Okamoto, Yoshihiro, et al.
Publicado: (2005)

TGF-beta expression in the human colon: differential immunostaining along crypt epithelium.
por: Avery, A., et al.
Publicado: (1993)

β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive efficacy of aspirin?
por: Smartt, H J M, et al.
Publicado: (2012)

Elevated transforming growth factor-beta 1 (TGF-β1) levels in human fracture healing()
por: Sarahrudi, Kambiz, et al.
Publicado: (2011)

TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study
por: Bacman, David, et al.
Publicado: (2007)

FKBP51 increases the tumour-promoter potential of TGF-beta
por: Romano, Simona, et al.
Publicado: (2014)

Circulating prostaglandins as biomarkers for colorectal cancer?
por: Greenhough, Alexander, et al.
Publicado: (2015)

Osteoblasts synthesize and respond to transforming growth factor-type beta (TGF-beta) in vitro
Publicado: (1987)

Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein
Publicado: (1994)

Mechanical stress contributes to osteoarthritis development through the activation of transforming growth factor beta 1 (TGF-β1)
por: Zhang, R-K., et al.
Publicado: (2018)

'Correction:' Serum transforming growth factor beta-1 (TGF-beta-1) levels in diabetic patients are not associated with pre-existent coronary artery disease
por: Schaan, Beatriz D, et al.
Publicado: (2007)

BAG3 induces fibroblasts to release key cytokines involved in pancreatic cell migration
por: Dufrusine, Beatrice, et al.
Publicado: (2021)

Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor beta (TGF-beta)
Publicado: (1991)

The role of transforming growth factor-beta (TGF-beta) during ovarian follicular development in sheep
por: Juengel, Jennifer L, et al.
Publicado: (2004)

Transforming Growth Factor-Beta (TGFβ) Signaling Pathway in Cholangiocarcinoma
por: Papoutsoglou, Panagiotis, et al.
Publicado: (2019)

Transforming growth factor beta 1 (TGF-β1) in COVID-19 patients: relation to platelets and association with the disease outcome
por: Zivancevic-Simonovic, Snezana, et al.
Publicado: (2023)

Modulation of Huntingtin Toxicity by BAG1 is Dependent on an Intact BAG Domain
por: Liman, Jan, et al.
Publicado: (2010)

Dynamics of Transforming Growth Factor (TGF)-β Superfamily Cytokine Induction During HIV-1 Infection Are Distinct From Other Innate Cytokines
por: Dickinson, Matthew, et al.
Publicado: (2020)

Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development
Publicado: (1991)

Transforming growth factor beta (TGF-β) in adolescent chronic fatigue syndrome
por: Wyller, Vegard Bruun, et al.
Publicado: (2017)

A transforming growth factor beta 2 (TGF-beta 2)-like immunosuppressive factor in amniotic fluid and localization of TGF-beta 2 mRNA in the pregnant uterus
Publicado: (1990)

Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1
por: Dong, Chunmin, et al.
Publicado: (2016)

Phorbol ester and bryostatin effects on growth and the expression of oestrogen responsive and TGF-beta 1 genes in breast tumour cells.
por: Nutt, J. E., et al.
Publicado: (1991)

Cannot write session to /tmp/vufind_sessions/sess_arlfmqg1hd3u2gl57hqgqm6cm6