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Metformin inhibits proliferation of human keratinocytes through a mechanism associated with activation of the MAPK signaling pathway
In the present study, the effects of metformin on the proliferation of human immortalized keratinocytes (HaCaTs) and the underlying mechanisms were investigated. HaCaT cells in the logarithmic growth phase were treated with 50 mM metformin for 24, 48 and 72 h. Cell morphology after 24 h of treatment...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881035/ https://www.ncbi.nlm.nih.gov/pubmed/24396411 http://dx.doi.org/10.3892/etm.2013.1416 |