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Radiation-induced cytochrome c release and the neuroprotective effects of the pan-caspase inhibitor z-VAD-fmk in the hypoglossal nucleus

Numerous studies have demonstrated that neuronal cell death occurs via extrinsic (death receptors) and intrinsic (mitochondria) pathways. Radiation induces caspase activation fundamentally via the mitochondrial pathway. To investigate the role of caspase, a cell permeable pan-caspase inhibitor, z-VA...

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Detalles Bibliográficos
Autores principales:	LI, JIANGUO, WANG, YAN, DU, LIQING, XU, CHANG, CAO, JIA, WANG, QIN, LIU, QIANG, FAN, FEIYUE
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881038/ https://www.ncbi.nlm.nih.gov/pubmed/24396410 http://dx.doi.org/10.3892/etm.2013.1419

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