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Preventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination
Surgical resection is the mainstay of treatment for solid tumors, but the postoperative period is uniquely inclined to the formation of metastases, largely due to the suppression of natural killer (NK) cells. We found that preoperative influenza vaccination prevents postoperative NK-cell dysfunction...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881108/ https://www.ncbi.nlm.nih.gov/pubmed/24404430 http://dx.doi.org/10.4161/onci.26618 |
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author | Tai, Lee-Hwa Zhang, Jiqing Auer, Rebecca C |
author_facet | Tai, Lee-Hwa Zhang, Jiqing Auer, Rebecca C |
author_sort | Tai, Lee-Hwa |
collection | PubMed |
description | Surgical resection is the mainstay of treatment for solid tumors, but the postoperative period is uniquely inclined to the formation of metastases, largely due to the suppression of natural killer (NK) cells. We found that preoperative influenza vaccination prevents postoperative NK-cell dysfunction, attenuating tumor dissemination in murine models and promoting the activation of NK cells in cancer patients. |
format | Online Article Text |
id | pubmed-3881108 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Landes Bioscience |
record_format | MEDLINE/PubMed |
spelling | pubmed-38811082014-01-08 Preventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination Tai, Lee-Hwa Zhang, Jiqing Auer, Rebecca C Oncoimmunology Author's View Surgical resection is the mainstay of treatment for solid tumors, but the postoperative period is uniquely inclined to the formation of metastases, largely due to the suppression of natural killer (NK) cells. We found that preoperative influenza vaccination prevents postoperative NK-cell dysfunction, attenuating tumor dissemination in murine models and promoting the activation of NK cells in cancer patients. Landes Bioscience 2013-11-01 2013-10-10 /pmc/articles/PMC3881108/ /pubmed/24404430 http://dx.doi.org/10.4161/onci.26618 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Author's View Tai, Lee-Hwa Zhang, Jiqing Auer, Rebecca C Preventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination |
title | Preventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination |
title_full | Preventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination |
title_fullStr | Preventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination |
title_full_unstemmed | Preventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination |
title_short | Preventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination |
title_sort | preventing surgery-induced nk cell dysfunction and cancer metastases with influenza vaccination |
topic | Author's View |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881108/ https://www.ncbi.nlm.nih.gov/pubmed/24404430 http://dx.doi.org/10.4161/onci.26618 |
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