Cargando…

Impact and Cost-Effectiveness of a Comprehensive Schistosomiasis japonica Control Program in the Poyang Lake Region of China

Schistosomiasis japonica remains a significant public-health problem in China. This study evaluated cost-effectiveness of a comprehensive schistosomiasis control program (2003–2006). The comprehensive control program was implemented in Zhangjia and Jianwu (cases); while standard interventions contin...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Qing, Zhao, Geng-Ming, Hong, Xian-Lin, Lutz, Eric A., Guo, Jia-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881122/
https://www.ncbi.nlm.nih.gov/pubmed/24287861
http://dx.doi.org/10.3390/ijerph10126409
_version_ 1782298166773678080
author Yu, Qing
Zhao, Geng-Ming
Hong, Xian-Lin
Lutz, Eric A.
Guo, Jia-Gang
author_facet Yu, Qing
Zhao, Geng-Ming
Hong, Xian-Lin
Lutz, Eric A.
Guo, Jia-Gang
author_sort Yu, Qing
collection PubMed
description Schistosomiasis japonica remains a significant public-health problem in China. This study evaluated cost-effectiveness of a comprehensive schistosomiasis control program (2003–2006). The comprehensive control program was implemented in Zhangjia and Jianwu (cases); while standard interventions continued in Koutou and Xiajia (controls). Incurred costs were documented and the schistosomiasis comprehensive impact index (SCI) and cost-effectiveness ratio (Comprehensive Control Program Cost/SCI) were applied. In 2003, prevalence of Schistosoma japonicum infection was 11.3% (Zhangjia), 6.7% (Jianwu), 6.5% (Koutou), and 8.0% (Xiajia). In 2006, the comprehensive control program in Zhangjia and Jianwu reduced infection to 1.6% and 0.6%, respectively; while Koutou and Xiajia had a schistosomiasis prevalence of 3.2% and 13.0%, respectively. The year-by-year SCIs in Zhangjia were 0.28, 105.25, and 47.58, with an overall increase in cost-effectiveness ratio of 374.9%–544.8%. The SCIs in Jianwu were 16.21, 52.95, and 149.58, with increase in cost-effectiveness of 226.7%–1,149.4%. Investment in Koutou and Xiajia remained static (US$10,000 unit cost). The comprehensive control program implemented in the two case villages reduced median prevalence of schistosomiasis 8.5-fold. Further, the cost effectiveness ratio demonstrated that the comprehensive control program was 170% (Zhangjia) and 922.7% (Jianwu) more cost-effective. This work clearly shows the improvements in both cost and disease prevention effectiveness that a comprehensive control program-approach has on schistosomiasis infection prevalence.
format Online
Article
Text
id pubmed-3881122
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-38811222014-01-06 Impact and Cost-Effectiveness of a Comprehensive Schistosomiasis japonica Control Program in the Poyang Lake Region of China Yu, Qing Zhao, Geng-Ming Hong, Xian-Lin Lutz, Eric A. Guo, Jia-Gang Int J Environ Res Public Health Article Schistosomiasis japonica remains a significant public-health problem in China. This study evaluated cost-effectiveness of a comprehensive schistosomiasis control program (2003–2006). The comprehensive control program was implemented in Zhangjia and Jianwu (cases); while standard interventions continued in Koutou and Xiajia (controls). Incurred costs were documented and the schistosomiasis comprehensive impact index (SCI) and cost-effectiveness ratio (Comprehensive Control Program Cost/SCI) were applied. In 2003, prevalence of Schistosoma japonicum infection was 11.3% (Zhangjia), 6.7% (Jianwu), 6.5% (Koutou), and 8.0% (Xiajia). In 2006, the comprehensive control program in Zhangjia and Jianwu reduced infection to 1.6% and 0.6%, respectively; while Koutou and Xiajia had a schistosomiasis prevalence of 3.2% and 13.0%, respectively. The year-by-year SCIs in Zhangjia were 0.28, 105.25, and 47.58, with an overall increase in cost-effectiveness ratio of 374.9%–544.8%. The SCIs in Jianwu were 16.21, 52.95, and 149.58, with increase in cost-effectiveness of 226.7%–1,149.4%. Investment in Koutou and Xiajia remained static (US$10,000 unit cost). The comprehensive control program implemented in the two case villages reduced median prevalence of schistosomiasis 8.5-fold. Further, the cost effectiveness ratio demonstrated that the comprehensive control program was 170% (Zhangjia) and 922.7% (Jianwu) more cost-effective. This work clearly shows the improvements in both cost and disease prevention effectiveness that a comprehensive control program-approach has on schistosomiasis infection prevalence. MDPI 2013-11-28 2013-12 /pmc/articles/PMC3881122/ /pubmed/24287861 http://dx.doi.org/10.3390/ijerph10126409 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Yu, Qing
Zhao, Geng-Ming
Hong, Xian-Lin
Lutz, Eric A.
Guo, Jia-Gang
Impact and Cost-Effectiveness of a Comprehensive Schistosomiasis japonica Control Program in the Poyang Lake Region of China
title Impact and Cost-Effectiveness of a Comprehensive Schistosomiasis japonica Control Program in the Poyang Lake Region of China
title_full Impact and Cost-Effectiveness of a Comprehensive Schistosomiasis japonica Control Program in the Poyang Lake Region of China
title_fullStr Impact and Cost-Effectiveness of a Comprehensive Schistosomiasis japonica Control Program in the Poyang Lake Region of China
title_full_unstemmed Impact and Cost-Effectiveness of a Comprehensive Schistosomiasis japonica Control Program in the Poyang Lake Region of China
title_short Impact and Cost-Effectiveness of a Comprehensive Schistosomiasis japonica Control Program in the Poyang Lake Region of China
title_sort impact and cost-effectiveness of a comprehensive schistosomiasis japonica control program in the poyang lake region of china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881122/
https://www.ncbi.nlm.nih.gov/pubmed/24287861
http://dx.doi.org/10.3390/ijerph10126409
work_keys_str_mv AT yuqing impactandcosteffectivenessofacomprehensiveschistosomiasisjaponicacontrolprograminthepoyanglakeregionofchina
AT zhaogengming impactandcosteffectivenessofacomprehensiveschistosomiasisjaponicacontrolprograminthepoyanglakeregionofchina
AT hongxianlin impactandcosteffectivenessofacomprehensiveschistosomiasisjaponicacontrolprograminthepoyanglakeregionofchina
AT lutzerica impactandcosteffectivenessofacomprehensiveschistosomiasisjaponicacontrolprograminthepoyanglakeregionofchina
AT guojiagang impactandcosteffectivenessofacomprehensiveschistosomiasisjaponicacontrolprograminthepoyanglakeregionofchina