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Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease

In advanced Parkinson's disease (PD), deep brain stimulation (DBS) may be an alternative option for the treatment of motor symptoms. Side effects associated with subthalamic nucleus (STN) DBS in patients with PD are emerging as the most frequent sensory and motor symptoms. DBS-related syncope i...

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Autores principales: Aygun, Dursun, Kocabicak, Ersoy, Yildiz, Onur, Onar, Musa Kazim, Guz, Hatice, Boke, Omer, Kurt, Murat, Temel, Yasin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881384/
https://www.ncbi.nlm.nih.gov/pubmed/24455344
http://dx.doi.org/10.1155/2013/371929
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author Aygun, Dursun
Kocabicak, Ersoy
Yildiz, Onur
Onar, Musa Kazim
Guz, Hatice
Boke, Omer
Kurt, Murat
Temel, Yasin
author_facet Aygun, Dursun
Kocabicak, Ersoy
Yildiz, Onur
Onar, Musa Kazim
Guz, Hatice
Boke, Omer
Kurt, Murat
Temel, Yasin
author_sort Aygun, Dursun
collection PubMed
description In advanced Parkinson's disease (PD), deep brain stimulation (DBS) may be an alternative option for the treatment of motor symptoms. Side effects associated with subthalamic nucleus (STN) DBS in patients with PD are emerging as the most frequent sensory and motor symptoms. DBS-related syncope is reported as extremely rare. We wanted to discuss the mechanisms of syncope associated with STN DBS in a patient with Parkinson's disease. Case report. Sixty-three-year-old female patient is followed up with diagnosis of idiopathic Parkinson's disease for 6 years in our clinic. The patient has undergone STN DBS due to painful dystonia and drug resistant tremor. During the operation, when the left STN was stimulated at 5 milliampere (mAmp), the patient developed presyncopal symptoms. However, when the stimulation was stopped symptoms improved. During the early period after the operation, when the right STN was stimulated at 1.3 millivolts (mV), she developed the pre-yncopal symptoms and then syncope. Our case shows that STN DBS may lead to directly autonomic symptoms resulting in syncope during stimulation-on (stim-on).
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spelling pubmed-38813842014-01-20 Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease Aygun, Dursun Kocabicak, Ersoy Yildiz, Onur Onar, Musa Kazim Guz, Hatice Boke, Omer Kurt, Murat Temel, Yasin Case Rep Neurol Med Case Report In advanced Parkinson's disease (PD), deep brain stimulation (DBS) may be an alternative option for the treatment of motor symptoms. Side effects associated with subthalamic nucleus (STN) DBS in patients with PD are emerging as the most frequent sensory and motor symptoms. DBS-related syncope is reported as extremely rare. We wanted to discuss the mechanisms of syncope associated with STN DBS in a patient with Parkinson's disease. Case report. Sixty-three-year-old female patient is followed up with diagnosis of idiopathic Parkinson's disease for 6 years in our clinic. The patient has undergone STN DBS due to painful dystonia and drug resistant tremor. During the operation, when the left STN was stimulated at 5 milliampere (mAmp), the patient developed presyncopal symptoms. However, when the stimulation was stopped symptoms improved. During the early period after the operation, when the right STN was stimulated at 1.3 millivolts (mV), she developed the pre-yncopal symptoms and then syncope. Our case shows that STN DBS may lead to directly autonomic symptoms resulting in syncope during stimulation-on (stim-on). Hindawi Publishing Corporation 2013 2013-12-22 /pmc/articles/PMC3881384/ /pubmed/24455344 http://dx.doi.org/10.1155/2013/371929 Text en Copyright © 2013 Dursun Aygun et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Aygun, Dursun
Kocabicak, Ersoy
Yildiz, Onur
Onar, Musa Kazim
Guz, Hatice
Boke, Omer
Kurt, Murat
Temel, Yasin
Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease
title Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease
title_full Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease
title_fullStr Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease
title_full_unstemmed Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease
title_short Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease
title_sort syncope associated with subthalamic nucleus deep brain stimulation in a patient with parkinson's disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881384/
https://www.ncbi.nlm.nih.gov/pubmed/24455344
http://dx.doi.org/10.1155/2013/371929
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