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Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease
In advanced Parkinson's disease (PD), deep brain stimulation (DBS) may be an alternative option for the treatment of motor symptoms. Side effects associated with subthalamic nucleus (STN) DBS in patients with PD are emerging as the most frequent sensory and motor symptoms. DBS-related syncope i...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881384/ https://www.ncbi.nlm.nih.gov/pubmed/24455344 http://dx.doi.org/10.1155/2013/371929 |
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author | Aygun, Dursun Kocabicak, Ersoy Yildiz, Onur Onar, Musa Kazim Guz, Hatice Boke, Omer Kurt, Murat Temel, Yasin |
author_facet | Aygun, Dursun Kocabicak, Ersoy Yildiz, Onur Onar, Musa Kazim Guz, Hatice Boke, Omer Kurt, Murat Temel, Yasin |
author_sort | Aygun, Dursun |
collection | PubMed |
description | In advanced Parkinson's disease (PD), deep brain stimulation (DBS) may be an alternative option for the treatment of motor symptoms. Side effects associated with subthalamic nucleus (STN) DBS in patients with PD are emerging as the most frequent sensory and motor symptoms. DBS-related syncope is reported as extremely rare. We wanted to discuss the mechanisms of syncope associated with STN DBS in a patient with Parkinson's disease. Case report. Sixty-three-year-old female patient is followed up with diagnosis of idiopathic Parkinson's disease for 6 years in our clinic. The patient has undergone STN DBS due to painful dystonia and drug resistant tremor. During the operation, when the left STN was stimulated at 5 milliampere (mAmp), the patient developed presyncopal symptoms. However, when the stimulation was stopped symptoms improved. During the early period after the operation, when the right STN was stimulated at 1.3 millivolts (mV), she developed the pre-yncopal symptoms and then syncope. Our case shows that STN DBS may lead to directly autonomic symptoms resulting in syncope during stimulation-on (stim-on). |
format | Online Article Text |
id | pubmed-3881384 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-38813842014-01-20 Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease Aygun, Dursun Kocabicak, Ersoy Yildiz, Onur Onar, Musa Kazim Guz, Hatice Boke, Omer Kurt, Murat Temel, Yasin Case Rep Neurol Med Case Report In advanced Parkinson's disease (PD), deep brain stimulation (DBS) may be an alternative option for the treatment of motor symptoms. Side effects associated with subthalamic nucleus (STN) DBS in patients with PD are emerging as the most frequent sensory and motor symptoms. DBS-related syncope is reported as extremely rare. We wanted to discuss the mechanisms of syncope associated with STN DBS in a patient with Parkinson's disease. Case report. Sixty-three-year-old female patient is followed up with diagnosis of idiopathic Parkinson's disease for 6 years in our clinic. The patient has undergone STN DBS due to painful dystonia and drug resistant tremor. During the operation, when the left STN was stimulated at 5 milliampere (mAmp), the patient developed presyncopal symptoms. However, when the stimulation was stopped symptoms improved. During the early period after the operation, when the right STN was stimulated at 1.3 millivolts (mV), she developed the pre-yncopal symptoms and then syncope. Our case shows that STN DBS may lead to directly autonomic symptoms resulting in syncope during stimulation-on (stim-on). Hindawi Publishing Corporation 2013 2013-12-22 /pmc/articles/PMC3881384/ /pubmed/24455344 http://dx.doi.org/10.1155/2013/371929 Text en Copyright © 2013 Dursun Aygun et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Aygun, Dursun Kocabicak, Ersoy Yildiz, Onur Onar, Musa Kazim Guz, Hatice Boke, Omer Kurt, Murat Temel, Yasin Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease |
title | Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease |
title_full | Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease |
title_fullStr | Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease |
title_full_unstemmed | Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease |
title_short | Syncope Associated with Subthalamic Nucleus Deep Brain Stimulation in a Patient with Parkinson's Disease |
title_sort | syncope associated with subthalamic nucleus deep brain stimulation in a patient with parkinson's disease |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881384/ https://www.ncbi.nlm.nih.gov/pubmed/24455344 http://dx.doi.org/10.1155/2013/371929 |
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