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Bioactive Lysophosphatidylcholine 16:0 and 18:0 Are Elevated in Lungs of Asthmatic Subjects

PURPOSE: Asthma is a chronic inflammatory disease of the airways, and is associated with upregulation of phospholipase A(2) (PLA(2)), the enzyme that hydrolyzes phosphatidylcholine, producing lysophosphatidylcholine (LPC) and free fatty acids. LPC is a lipid mediator with known pro-inflammatory and...

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Detalles Bibliográficos
Autores principales:	Yoder, Mark, Zhuge, Yan, Yuan, Yang, Holian, Oksana, Kuo, Sherry, van Breemen, Richard, Thomas, Larry L., Lum, Hazel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881403/ https://www.ncbi.nlm.nih.gov/pubmed/24404395 http://dx.doi.org/10.4168/aair.2014.6.1.61

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