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Dendritic cell-based vaccines: Shining the spotlight on signal 3
Dendritic cell (DC)-based anticancer vaccines have yielded disappointing results in a multitude of clinical trials. New data suggest that the clinical efficacy of DC-based vaccines may be dependent on the paracrine production of interleukin-12 in the course of antigen presentation and the consequent...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881596/ https://www.ncbi.nlm.nih.gov/pubmed/24404428 http://dx.doi.org/10.4161/onci.26512 |
| _version_ | 1782298239067750400 |
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| author | Linette, Gerald P Carreno, Beatriz M |
| author_facet | Linette, Gerald P Carreno, Beatriz M |
| author_sort | Linette, Gerald P |
| collection | PubMed |
| description | Dendritic cell (DC)-based anticancer vaccines have yielded disappointing results in a multitude of clinical trials. New data suggest that the clinical efficacy of DC-based vaccines may be dependent on the paracrine production of interleukin-12 in the course of antigen presentation and the consequent development of therapeutic Type 1 CD8(+) T-cell immunity. |
| format | Online Article Text |
| id | pubmed-3881596 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | Landes Bioscience |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-38815962014-01-08 Dendritic cell-based vaccines: Shining the spotlight on signal 3 Linette, Gerald P Carreno, Beatriz M Oncoimmunology Author's View Dendritic cell (DC)-based anticancer vaccines have yielded disappointing results in a multitude of clinical trials. New data suggest that the clinical efficacy of DC-based vaccines may be dependent on the paracrine production of interleukin-12 in the course of antigen presentation and the consequent development of therapeutic Type 1 CD8(+) T-cell immunity. Landes Bioscience 2013-11-01 2013-10-10 /pmc/articles/PMC3881596/ /pubmed/24404428 http://dx.doi.org/10.4161/onci.26512 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
| spellingShingle | Author's View Linette, Gerald P Carreno, Beatriz M Dendritic cell-based vaccines: Shining the spotlight on signal 3 |
| title | Dendritic cell-based vaccines: Shining the spotlight on signal 3 |
| title_full | Dendritic cell-based vaccines: Shining the spotlight on signal 3 |
| title_fullStr | Dendritic cell-based vaccines: Shining the spotlight on signal 3 |
| title_full_unstemmed | Dendritic cell-based vaccines: Shining the spotlight on signal 3 |
| title_short | Dendritic cell-based vaccines: Shining the spotlight on signal 3 |
| title_sort | dendritic cell-based vaccines: shining the spotlight on signal 3 |
| topic | Author's View |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881596/ https://www.ncbi.nlm.nih.gov/pubmed/24404428 http://dx.doi.org/10.4161/onci.26512 |
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