Interaction of JAK with steroid receptor function

The function of steroid receptors is not only regulated by steroid hormones, but also by multiple cellular signaling cascades activated by membrane-bound receptors which are stimulated by growth factors or cytokines. Cross-talk between JAK and steroid receptors plays a central role in the regulation...

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Detalles Bibliográficos
Autores principales: Gupta, Nibedita, Mayer, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881601/
https://www.ncbi.nlm.nih.gov/pubmed/24416641
http://dx.doi.org/10.4161/jkst.24911
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author Gupta, Nibedita
Mayer, Doris
author_facet Gupta, Nibedita
Mayer, Doris
author_sort Gupta, Nibedita
collection PubMed
description The function of steroid receptors is not only regulated by steroid hormones, but also by multiple cellular signaling cascades activated by membrane-bound receptors which are stimulated by growth factors or cytokines. Cross-talk between JAK and steroid receptors plays a central role in the regulation of a multitude of physiological processes and aberrant signaling is involved in the development of numerous diseases including cancer. In this review we provide a brief summary of the knowledge of interactions between JAK and the function of steroid receptors in normal cells and tissues and in diseases.
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spelling pubmed-38816012014-01-10 Interaction of JAK with steroid receptor function Gupta, Nibedita Mayer, Doris JAKSTAT Review The function of steroid receptors is not only regulated by steroid hormones, but also by multiple cellular signaling cascades activated by membrane-bound receptors which are stimulated by growth factors or cytokines. Cross-talk between JAK and steroid receptors plays a central role in the regulation of a multitude of physiological processes and aberrant signaling is involved in the development of numerous diseases including cancer. In this review we provide a brief summary of the knowledge of interactions between JAK and the function of steroid receptors in normal cells and tissues and in diseases. Landes Bioscience 2013-10-01 2013-05-07 /pmc/articles/PMC3881601/ /pubmed/24416641 http://dx.doi.org/10.4161/jkst.24911 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Review
Gupta, Nibedita
Mayer, Doris
Interaction of JAK with steroid receptor function
title Interaction of JAK with steroid receptor function
title_full Interaction of JAK with steroid receptor function
title_fullStr Interaction of JAK with steroid receptor function
title_full_unstemmed Interaction of JAK with steroid receptor function
title_short Interaction of JAK with steroid receptor function
title_sort interaction of jak with steroid receptor function
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881601/
https://www.ncbi.nlm.nih.gov/pubmed/24416641
http://dx.doi.org/10.4161/jkst.24911
work_keys_str_mv AT guptanibedita interactionofjakwithsteroidreceptorfunction
AT mayerdoris interactionofjakwithsteroidreceptorfunction

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