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Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes

Our aim was to evaluate the long-term efficacy and safety of percutaneous transhepatic obliteration (PTO) alone and combined with balloon-occluded retrograde transvenous obliteration (BRTO) for gastroesophageal varices refractory to BRTO alone. Between July 1999 and December 2010, 13 patients with g...

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Autores principales: Uchiyama, Fumio, Murata, Satoru, Onozawa, Shiro, Nakazawa, Ken, Sugihara, Fumie, Yasui, Daisuke, Narahara, Yoshiyuki, Uchida, Eiji, Amano, Yasuo, Kumita, Shin-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881666/
https://www.ncbi.nlm.nih.gov/pubmed/24453866
http://dx.doi.org/10.1155/2013/498535
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author Uchiyama, Fumio
Murata, Satoru
Onozawa, Shiro
Nakazawa, Ken
Sugihara, Fumie
Yasui, Daisuke
Narahara, Yoshiyuki
Uchida, Eiji
Amano, Yasuo
Kumita, Shin-ichiro
author_facet Uchiyama, Fumio
Murata, Satoru
Onozawa, Shiro
Nakazawa, Ken
Sugihara, Fumie
Yasui, Daisuke
Narahara, Yoshiyuki
Uchida, Eiji
Amano, Yasuo
Kumita, Shin-ichiro
author_sort Uchiyama, Fumio
collection PubMed
description Our aim was to evaluate the long-term efficacy and safety of percutaneous transhepatic obliteration (PTO) alone and combined with balloon-occluded retrograde transvenous obliteration (BRTO) for gastroesophageal varices refractory to BRTO alone. Between July 1999 and December 2010, 13 patients with gastroesophageal varices refractory to BRTO were treated with PTO (n = 6) or a combination of PTO and BRTO (n = 7). We retrospectively investigated the rates of survival, recurrence, or worsening of the varices; hepatic function before and after the procedure; and complications. The procedure achieved complete obliteration or significant reduction of the varices in all 13 patients without major complications. During follow-up, the varices had recurred in 2 patients, of which one had hepatocellular carcinoma, and the other died suddenly from variceal rebleeding 7 years after PTO. The remaining 11 patients did not experience worsening of the varices and showed significant improvements in the serum ammonia levels and prothrombin time. The mean follow-up period was 90 months, and the cumulative survival rate at 1, 3, and 5 years was 92.9%, 85.7%, and 85.7%, respectively. Both PTO and combined PTO and BRTO seem as safe and effective procedures for the treatment of gastroesophageal varices refractory to BRTO alone.
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spelling pubmed-38816662014-01-20 Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes Uchiyama, Fumio Murata, Satoru Onozawa, Shiro Nakazawa, Ken Sugihara, Fumie Yasui, Daisuke Narahara, Yoshiyuki Uchida, Eiji Amano, Yasuo Kumita, Shin-ichiro ScientificWorldJournal Research Article Our aim was to evaluate the long-term efficacy and safety of percutaneous transhepatic obliteration (PTO) alone and combined with balloon-occluded retrograde transvenous obliteration (BRTO) for gastroesophageal varices refractory to BRTO alone. Between July 1999 and December 2010, 13 patients with gastroesophageal varices refractory to BRTO were treated with PTO (n = 6) or a combination of PTO and BRTO (n = 7). We retrospectively investigated the rates of survival, recurrence, or worsening of the varices; hepatic function before and after the procedure; and complications. The procedure achieved complete obliteration or significant reduction of the varices in all 13 patients without major complications. During follow-up, the varices had recurred in 2 patients, of which one had hepatocellular carcinoma, and the other died suddenly from variceal rebleeding 7 years after PTO. The remaining 11 patients did not experience worsening of the varices and showed significant improvements in the serum ammonia levels and prothrombin time. The mean follow-up period was 90 months, and the cumulative survival rate at 1, 3, and 5 years was 92.9%, 85.7%, and 85.7%, respectively. Both PTO and combined PTO and BRTO seem as safe and effective procedures for the treatment of gastroesophageal varices refractory to BRTO alone. Hindawi Publishing Corporation 2013-12-21 /pmc/articles/PMC3881666/ /pubmed/24453866 http://dx.doi.org/10.1155/2013/498535 Text en Copyright © 2013 Fumio Uchiyama et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Uchiyama, Fumio
Murata, Satoru
Onozawa, Shiro
Nakazawa, Ken
Sugihara, Fumie
Yasui, Daisuke
Narahara, Yoshiyuki
Uchida, Eiji
Amano, Yasuo
Kumita, Shin-ichiro
Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes
title Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes
title_full Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes
title_fullStr Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes
title_full_unstemmed Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes
title_short Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes
title_sort management of gastric varices unsuccessfully treated by balloon-occluded retrograde transvenous obliteration: long-term follow-up and outcomes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881666/
https://www.ncbi.nlm.nih.gov/pubmed/24453866
http://dx.doi.org/10.1155/2013/498535
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