Cargando…

Histomorphometric analysis of the temporal bone after change of direction of force vector of mandible: an experimental study in rabbits

OBJECTIVES: The present study aimed at performing a histological evaluation of the response of temporal bone tissue to a change of direction of the force vector of the mandible in relation to the base of the skull. MATERIAL AND METHODS: Adult rabbits were assigned into four groups with two control a...

Descripción completa

Detalles Bibliográficos
Autores principales: PURICELLI, Edela, PONZONI, Deise, MUNARETTO, Jéssica Cerioli, CORSETTI, Adriana, LEITE, Mauro Gomes Trein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Odontologia de Bauru da Universidade de São Paulo 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881785/
https://www.ncbi.nlm.nih.gov/pubmed/23138738
http://dx.doi.org/10.1590/S1678-77572012000500006
_version_ 1782298263589748736
author PURICELLI, Edela
PONZONI, Deise
MUNARETTO, Jéssica Cerioli
CORSETTI, Adriana
LEITE, Mauro Gomes Trein
author_facet PURICELLI, Edela
PONZONI, Deise
MUNARETTO, Jéssica Cerioli
CORSETTI, Adriana
LEITE, Mauro Gomes Trein
author_sort PURICELLI, Edela
collection PubMed
description OBJECTIVES: The present study aimed at performing a histological evaluation of the response of temporal bone tissue to a change of direction of the force vector of the mandible in relation to the base of the skull. MATERIAL AND METHODS: Adult rabbits were assigned into four groups with two control and four experimental animals in each group. Experimental animals underwent surgery, which resulted in a change of direction of the force vector on the right temporomandibular joint. Samples were collected after 15, 30, 60 and 90 days for histological analysis. RESULTS: In the two-way analysis of variance, the effect of group and time was statistically significant (p<0.001). Additionally, a statistically significant interaction between group and time was observed (p<0.001). Control animals showed normal growth and development of the temporal region. In the experimental group, the change in direction of the force vector of the mandible induced significant changes in the temporal bone, with a bone modeling process, which suggests growth of this cranial structure. CONCLUSIONS: The methodology used in this experiment allows us to conclude that the change in direction of the force vector of the mandible in relation to the skull base induces remodeling and modeling processes in the temporal bone. The resumption of normal oral functions after bone healing of the mandibular fracture appears to increase cell activation in the remodeling and modeling of the temporal bone structure. The observation of areas of temporal bone modeling shows the relevance of further investigation on the correlation between the joint structures and craniofacial growth and development.
format Online
Article
Text
id pubmed-3881785
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Faculdade de Odontologia de Bauru da Universidade de São Paulo
record_format MEDLINE/PubMed
spelling pubmed-38817852014-01-08 Histomorphometric analysis of the temporal bone after change of direction of force vector of mandible: an experimental study in rabbits PURICELLI, Edela PONZONI, Deise MUNARETTO, Jéssica Cerioli CORSETTI, Adriana LEITE, Mauro Gomes Trein J Appl Oral Sci Original Articles OBJECTIVES: The present study aimed at performing a histological evaluation of the response of temporal bone tissue to a change of direction of the force vector of the mandible in relation to the base of the skull. MATERIAL AND METHODS: Adult rabbits were assigned into four groups with two control and four experimental animals in each group. Experimental animals underwent surgery, which resulted in a change of direction of the force vector on the right temporomandibular joint. Samples were collected after 15, 30, 60 and 90 days for histological analysis. RESULTS: In the two-way analysis of variance, the effect of group and time was statistically significant (p<0.001). Additionally, a statistically significant interaction between group and time was observed (p<0.001). Control animals showed normal growth and development of the temporal region. In the experimental group, the change in direction of the force vector of the mandible induced significant changes in the temporal bone, with a bone modeling process, which suggests growth of this cranial structure. CONCLUSIONS: The methodology used in this experiment allows us to conclude that the change in direction of the force vector of the mandible in relation to the skull base induces remodeling and modeling processes in the temporal bone. The resumption of normal oral functions after bone healing of the mandibular fracture appears to increase cell activation in the remodeling and modeling of the temporal bone structure. The observation of areas of temporal bone modeling shows the relevance of further investigation on the correlation between the joint structures and craniofacial growth and development. Faculdade de Odontologia de Bauru da Universidade de São Paulo 2012 /pmc/articles/PMC3881785/ /pubmed/23138738 http://dx.doi.org/10.1590/S1678-77572012000500006 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
PURICELLI, Edela
PONZONI, Deise
MUNARETTO, Jéssica Cerioli
CORSETTI, Adriana
LEITE, Mauro Gomes Trein
Histomorphometric analysis of the temporal bone after change of direction of force vector of mandible: an experimental study in rabbits
title Histomorphometric analysis of the temporal bone after change of direction of force vector of mandible: an experimental study in rabbits
title_full Histomorphometric analysis of the temporal bone after change of direction of force vector of mandible: an experimental study in rabbits
title_fullStr Histomorphometric analysis of the temporal bone after change of direction of force vector of mandible: an experimental study in rabbits
title_full_unstemmed Histomorphometric analysis of the temporal bone after change of direction of force vector of mandible: an experimental study in rabbits
title_short Histomorphometric analysis of the temporal bone after change of direction of force vector of mandible: an experimental study in rabbits
title_sort histomorphometric analysis of the temporal bone after change of direction of force vector of mandible: an experimental study in rabbits
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881785/
https://www.ncbi.nlm.nih.gov/pubmed/23138738
http://dx.doi.org/10.1590/S1678-77572012000500006
work_keys_str_mv AT puricelliedela histomorphometricanalysisofthetemporalboneafterchangeofdirectionofforcevectorofmandibleanexperimentalstudyinrabbits
AT ponzonideise histomorphometricanalysisofthetemporalboneafterchangeofdirectionofforcevectorofmandibleanexperimentalstudyinrabbits
AT munarettojessicacerioli histomorphometricanalysisofthetemporalboneafterchangeofdirectionofforcevectorofmandibleanexperimentalstudyinrabbits
AT corsettiadriana histomorphometricanalysisofthetemporalboneafterchangeofdirectionofforcevectorofmandibleanexperimentalstudyinrabbits
AT leitemaurogomestrein histomorphometricanalysisofthetemporalboneafterchangeofdirectionofforcevectorofmandibleanexperimentalstudyinrabbits