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Adenovirus-mediated delivery of the human IFN-γ gene potentiates the cytotoxicity of daunorubicin against leukemic cells through downregulation of the α4β1 integrin/ILK/apoptosis pathway

The recurrence of acute myeloid leukemia (AML) is primarily attributed to drug resistance and minimal residual disease. In addition, adhesion of hematopoietic tumor cells to bone marrow extracellular matrix via β1 integrins (α4β1 and α5β1) is crucial in this process. In the current study, the viabil...

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Detalles Bibliográficos
Autores principales:	ZHANG, JING, WANG, HUA, WANG, LIANG, WANG, WEI-DA, GENG, QI-RONG, LU, YUE
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881933/ https://www.ncbi.nlm.nih.gov/pubmed/24396448 http://dx.doi.org/10.3892/ol.2013.1749

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