Gradient Boosting as a SNP Filter: an Evaluation Using Simulated and Hair Morphology Data

Typically, genome-wide association studies consist of regressing the phenotype on each SNP separately using an additive genetic model. Although statistical models for recessive, dominant, SNP-SNP, or SNP-environment interactions exist, the testing burden makes an evaluation of all possible effects i...

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Detalles Bibliográficos
Autores principales: Lubke, GH, Laurin, C, Walters, R, Eriksson, N, Hysi, P, Spector, TD, Montgomery, GW, Martin, NG, Medland, SE, Boomsma, DI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882018/
https://www.ncbi.nlm.nih.gov/pubmed/24404405
http://dx.doi.org/10.4172/2153-0602.1000143

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