Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library

Cell migration is fundamental to the inflammatory response, but uncontrolled cell migration and excess recruitment of neutrophils and other leukocytes can cause damage to the tissue. Here we describe the use of an in vivo model – the Tg(mpx:GFP)(i114) zebrafish line, in which neutrophils are labelle...

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Detalles Bibliográficos
Autores principales: Wang, Xingang, Robertson, Anne L., Li, Jingyu, Chai, Ruth Jinfen, Haishan, Wang, Sadiku, Pranvera, Ogryzko, Nikolay V., Everett, Martin, Yoganathan, Kanagasundaram, Luo, Hongbo Robert, Renshaw, Stephen A., Ingham, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882058/
https://www.ncbi.nlm.nih.gov/pubmed/24291762
http://dx.doi.org/10.1242/dmm.012047

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