The La antigen is over-expressed in lung cancer and is a selective dead cancer cell target for radioimmunotherapy using the La-specific antibody APOMAB®

BACKGROUND: The lupus-associated (La)-specific murine monoclonal antibody DAB4 (APOMAB®) specifically binds dead cancer cells. Using DAB4, we examined La expression in human lung cancer samples to assess its suitability as a cancer-selective therapeutic target. We evaluated the safety and effectiven...

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Detalles Bibliográficos
Autores principales: Staudacher, Alexander H, Al-Ejeh, Fares, Fraser, Cara K, Darby, Jocelyn M, Roder, David M, Ruszkiewicz, Andrew, Manavis, Jim, Brown, Michael P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882100/
https://www.ncbi.nlm.nih.gov/pubmed/24387284
http://dx.doi.org/10.1186/2191-219X-4-2

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