Drugging a Stem Cell Compartment Using Wnt3a Protein as a Therapeutic

The therapeutic potential of Wnt proteins has long been recognized but challenges associated with in vivo stability and delivery have hindered their development as drug candidates. By exploiting the hydrophobic nature of the protein we provide evidence that exogenous Wnt3a can be delivered in vivo i...

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Detalles Bibliográficos
Autores principales: Dhamdhere, Girija R., Fang, Mark Y., Jiang, Jie, Lee, Katherine, Cheng, Du, Olveda, Rebecca C., Liu, Bo, Mulligan, Kimberley A., Carlson, Jeffery C., Ransom, Ryan C., Weis, William I., Helms, Jill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882211/
https://www.ncbi.nlm.nih.gov/pubmed/24400074
http://dx.doi.org/10.1371/journal.pone.0083650

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