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Combined Therapy of Iron Chelator and Antioxidant Completely Restores Brain Dysfunction Induced by Iron Toxicity

BACKGROUND: Excessive iron accumulation leads to iron toxicity in the brain; however the underlying mechanism is unclear. We investigated the effects of iron overload induced by high iron-diet consumption on brain mitochondrial function, brain synaptic plasticity and learning and memory. Iron chelat...

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Detalles Bibliográficos
Autores principales:	Sripetchwandee, Jirapas, Pipatpiboon, Noppamas, Chattipakorn, Nipon, Chattipakorn, Siriporn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882264/ https://www.ncbi.nlm.nih.gov/pubmed/24400127 http://dx.doi.org/10.1371/journal.pone.0085115

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