Full-Genome Analysis of a Canine Pneumovirus Causing Acute Respiratory Disease in Dogs, Italy

An outbreak of canine infectious respiratory disease (CIRD) associated to canine pneumovirus (CnPnV) infection is reported. The outbreak occurred in a shelter of the Apulia region and involved 37 out of 350 dogs that displayed cough and/or nasal discharge with no evidence of fever. The full-genomic...

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Autores principales: Decaro, Nicola, Pinto, Pierfrancesco, Mari, Viviana, Elia, Gabriella, Larocca, Vittorio, Camero, Michele, Terio, Valentina, Losurdo, Michele, Martella, Vito, Buonavoglia, Canio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882280/
https://www.ncbi.nlm.nih.gov/pubmed/24400129
http://dx.doi.org/10.1371/journal.pone.0085220
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author Decaro, Nicola
Pinto, Pierfrancesco
Mari, Viviana
Elia, Gabriella
Larocca, Vittorio
Camero, Michele
Terio, Valentina
Losurdo, Michele
Martella, Vito
Buonavoglia, Canio
author_facet Decaro, Nicola
Pinto, Pierfrancesco
Mari, Viviana
Elia, Gabriella
Larocca, Vittorio
Camero, Michele
Terio, Valentina
Losurdo, Michele
Martella, Vito
Buonavoglia, Canio
author_sort Decaro, Nicola
collection PubMed
description An outbreak of canine infectious respiratory disease (CIRD) associated to canine pneumovirus (CnPnV) infection is reported. The outbreak occurred in a shelter of the Apulia region and involved 37 out of 350 dogs that displayed cough and/or nasal discharge with no evidence of fever. The full-genomic characterisation showed that the causative agent (strain Bari/100-12) was closely related to CnPnVs that have been recently isolated in the USA, as well as to murine pneumovirus, which is responsible for respiratory disease in mice. The present study represents a useful contribution to the knowledge of the pathogenic potential of CnPnV and its association with CIRD in dogs. Further studies will elucidate the pathogenicity and epidemiology of this novel pneumovirus, thus addressing the eventual need for specific vaccines.
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spelling pubmed-38822802014-01-07 Full-Genome Analysis of a Canine Pneumovirus Causing Acute Respiratory Disease in Dogs, Italy Decaro, Nicola Pinto, Pierfrancesco Mari, Viviana Elia, Gabriella Larocca, Vittorio Camero, Michele Terio, Valentina Losurdo, Michele Martella, Vito Buonavoglia, Canio PLoS One Research Article An outbreak of canine infectious respiratory disease (CIRD) associated to canine pneumovirus (CnPnV) infection is reported. The outbreak occurred in a shelter of the Apulia region and involved 37 out of 350 dogs that displayed cough and/or nasal discharge with no evidence of fever. The full-genomic characterisation showed that the causative agent (strain Bari/100-12) was closely related to CnPnVs that have been recently isolated in the USA, as well as to murine pneumovirus, which is responsible for respiratory disease in mice. The present study represents a useful contribution to the knowledge of the pathogenic potential of CnPnV and its association with CIRD in dogs. Further studies will elucidate the pathogenicity and epidemiology of this novel pneumovirus, thus addressing the eventual need for specific vaccines. Public Library of Science 2014-01-06 /pmc/articles/PMC3882280/ /pubmed/24400129 http://dx.doi.org/10.1371/journal.pone.0085220 Text en © 2014 Decaro et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Decaro, Nicola
Pinto, Pierfrancesco
Mari, Viviana
Elia, Gabriella
Larocca, Vittorio
Camero, Michele
Terio, Valentina
Losurdo, Michele
Martella, Vito
Buonavoglia, Canio
Full-Genome Analysis of a Canine Pneumovirus Causing Acute Respiratory Disease in Dogs, Italy
title Full-Genome Analysis of a Canine Pneumovirus Causing Acute Respiratory Disease in Dogs, Italy
title_full Full-Genome Analysis of a Canine Pneumovirus Causing Acute Respiratory Disease in Dogs, Italy
title_fullStr Full-Genome Analysis of a Canine Pneumovirus Causing Acute Respiratory Disease in Dogs, Italy
title_full_unstemmed Full-Genome Analysis of a Canine Pneumovirus Causing Acute Respiratory Disease in Dogs, Italy
title_short Full-Genome Analysis of a Canine Pneumovirus Causing Acute Respiratory Disease in Dogs, Italy
title_sort full-genome analysis of a canine pneumovirus causing acute respiratory disease in dogs, italy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882280/
https://www.ncbi.nlm.nih.gov/pubmed/24400129
http://dx.doi.org/10.1371/journal.pone.0085220
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