Reduced ADAMTS13 activity is associated with an ADAMTS13 SNP, fever and microparticles in a malaria-like model

BACKGROUND: Severe falciparum malaria (SM) remains a major cause of death in tropical countries. The reduced activity of ADAMTS13, increasing levels of ultra-large von Willebrand factor (ULVWF) in SM patients, are assumed as factors that intensify disease severity. However, the reason why ADAMTS13 a...

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Detalles Bibliográficos
Autores principales: Kraisin, Sirima, Palasuwan, Attakorn, Popruk, Supaluk, Nantakomol, Duangdao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882324/
https://www.ncbi.nlm.nih.gov/pubmed/24386898
http://dx.doi.org/10.1186/1475-2875-13-3

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