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TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability

DNA anaphase bridges are a potential source of genome instability that may lead to chromosome breakage or nondisjunction during mitosis. Two classes of anaphase bridges can be distinguished: DAPI-positive chromatin bridges and DAPI-negative ultrafine DNA bridges (UFBs). Here, we establish budding ye...

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Detalles Bibliográficos
Autores principales:	Germann, Susanne M., Schramke, Vera, Pedersen, Rune Troelsgaard, Gallina, Irene, Eckert-Boulet, Nadine, Oestergaard, Vibe H., Lisby, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882784/ https://www.ncbi.nlm.nih.gov/pubmed/24379413 http://dx.doi.org/10.1083/jcb.201305157

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