Cargando…

Presynaptic CK2 promotes synapse organization and stability by targeting Ankyrin2

The precise regulation of synapse maintenance is critical to the development and function of neuronal circuits. Using an in vivo RNAi screen targeting the Drosophila kinome and phosphatome, we identify 11 kinases and phosphatases controlling synapse stability by regulating cytoskeletal, phospholipid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bulat, Victoria, Rast, Melanie, Pielage, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882785/ https://www.ncbi.nlm.nih.gov/pubmed/24395637 http://dx.doi.org/10.1083/jcb.201305134

Ejemplares similares

The Ankyrin Repeat Domain Controls Presynaptic Localization of Drosophila Ankyrin2 and Is Essential for Synaptic Stability
por: Weber, Tobias, et al.
Publicado: (2019)

Molecular mechanisms that enhance synapse stability despite persistent disruption of the spectrin/ankyrin/microtubule cytoskeleton
por: Massaro, Catherine M., et al.
Publicado: (2009)

Presynaptic α(2)δ subunits are key organizers of glutamatergic synapses
por: Schöpf, Clemens L., et al.
Publicado: (2021)

Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G
por: Bréchet, Aline, et al.
Publicado: (2008)

The presynaptic machinery at the synapse of C. elegans
por: Calahorro, Fernando, et al.
Publicado: (2018)

Structural Organization of the Presynaptic Density at Identified Synapses in the Locust Central Nervous System
por: Leitinger, Gerd, et al.
Publicado: (2012)

PTPσ Controls Presynaptic Organization of Neurotransmitter Release Machinery at Excitatory Synapses
por: Han, Kyung Ah, et al.
Publicado: (2020)

Presynaptically Silent Synapses Studied with Light Microscopy
por: Moulder, Krista L., et al.
Publicado: (2010)

Presynaptic Self-Depression at Developing Neocortical Synapses
por: Rodríguez-Moreno, Antonio, et al.
Publicado: (2013)

Presynaptic nanodomains: a tale of two synapses
por: Wang, Lu-Yang, et al.
Publicado: (2015)

Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons
por: Mosca, Timothy J, et al.
Publicado: (2017)

Presynaptic [Ca(2+)] and GCAPs: aspects on the structure and function of photoreceptor ribbon synapses
por: Schmitz, Frank
Publicado: (2014)

Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction
por: Weinhard, Laetitia, et al.
Publicado: (2018)

Synapse-specific and compartmentalized expression of presynaptic homeostatic potentiation
por: Li, Xiling, et al.
Publicado: (2018)

Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses
por: Maus, Lydia, et al.
Publicado: (2020)

Presynaptic potentials and facilitation of transmitter release in the squid giant synapse
Publicado: (1978)

Disrupted-in-Schizophrenia (DISC1) Functions Presynaptically at Glutamatergic Synapses
por: Maher, Brady J., et al.
Publicado: (2012)

Metal Toxicity at the Synapse: Presynaptic, Postsynaptic, and Long-Term Effects
por: Sadiq, Sanah, et al.
Publicado: (2012)

Neurexins regulate presynaptic GABA(B)-receptors at central synapses
por: Luo, Fujun, et al.
Publicado: (2021)

Similarity and Diversity of Presynaptic Molecules at Neuromuscular Junctions and Central Synapses
por: Takikawa, Kenji, et al.
Publicado: (2022)

Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands
por: Zhang, Xuchen, et al.
Publicado: (2022)

Ankyrin‐2 genetic variants: A case of Ankyrin‐B syndrome
por: Song, Jin, et al.
Publicado: (2022)

Ankyrin protein networks in membrane formation and stabilization
por: Cunha, Shane R, et al.
Publicado: (2009)

CK2 and protein kinases of the CK1 superfamily as targets for neurodegenerative disorders
por: Baier, Andrea, et al.
Publicado: (2022)

Presynaptic NMDA Receptors and Spike Timing-Dependent Depression at Cortical Synapses
por: Rodríguez-Moreno, Antonio, et al.
Publicado: (2010)

Lrp4 Is A Retrograde Signal For Presynaptic Differentiation At Neuromuscular Synapses
por: Yumoto, Norihiro, et al.
Publicado: (2012)

Synapses with short-term plasticity are optimal estimators of presynaptic membrane potentials
por: Pfister, Jean-Pascal, et al.
Publicado: (2010)

Inositol Pyrophosphate Metabolism Regulates Presynaptic Vesicle Cycling at Central Synapses
por: Park, Seung Ju, et al.
Publicado: (2020)

Rapid and sustained homeostatic control of presynaptic exocytosis at a central synapse
por: Delvendahl, Igor, et al.
Publicado: (2019)

Presynaptic endoplasmic reticulum regulates short-term plasticity in hippocampal synapses
por: Singh, Nishant, et al.
Publicado: (2021)

PTPδ is a presynaptic organizer for the formation and maintenance of climbing fiber to Purkinje cell synapses in the developing cerebellum
por: Okuno, Yuto, et al.
Publicado: (2023)

Chronic early life lead (Pb(2+)) exposure alters presynaptic vesicle pools in hippocampal synapses
por: Guariglia, Sara Rose, et al.
Publicado: (2016)

Multiplex imaging relates quantal glutamate release to presynaptic Ca(2+) homeostasis at multiple synapses in situ
por: Jensen, Thomas P., et al.
Publicado: (2019)

Synaptotagmin Ca(2+) Sensors and Their Spatial Coupling to Presynaptic Ca(v) Channels in Central Cortical Synapses
por: Bornschein, Grit, et al.
Publicado: (2019)

Neurexin-2 restricts synapse numbers and restrains the presynaptic release probability by an alternative splicing-dependent mechanism
por: Lin, Pei-Yi, et al.
Publicado: (2023)

Targeting Protein Kinases in Blood Cancer: Focusing on CK1α and CK2
por: Spinello, Zaira, et al.
Publicado: (2021)

Author Correction: Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands
por: Zhang, Xuchen, et al.
Publicado: (2023)

In vivo knockdown of Piccolino disrupts presynaptic ribbon morphology in mouse photoreceptor synapses
por: Regus-Leidig, Hanna, et al.
Publicado: (2014)

Translating neuronal activity at the synapse: presynaptic calcium sensors in short-term plasticity
por: de Jong, Arthur P. H., et al.
Publicado: (2014)

Presynaptic uptake blockade hypothesis for LSD action at the lateral inhibitory synapse in Limulus
Publicado: (1983)

Cannot write session to /tmp/vufind_sessions/sess_10gvkja69n3t3smauaqbiingn0