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Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation
Epithelial cells develop morphologically characteristic apical domains that are bordered by tight junctions, the apical–lateral border. Cdc42 and its effector complex Par6–atypical protein kinase c (aPKC) regulate multiple steps during epithelial differentiation, but the mechanisms that mediate proc...
Autores principales: | Zihni, Ceniz, Munro, Peter M.G., Elbediwy, Ahmed, Keep, Nicholas H., Terry, Stephen J., Harris, John, Balda, Maria S., Matter, Karl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882792/ https://www.ncbi.nlm.nih.gov/pubmed/24379416 http://dx.doi.org/10.1083/jcb.201304064 |
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