DABSO-Based, Three-Component, One-Pot Sulfone Synthesis

[Image: see text] The addition of Grignard reagents or organolithium reagents to the SO(2)-surrogate DABSO generates a diverse set of metal sulfinates, suitable for direct conversion to sulfone products. The metal sulfinates can be trapped in situ with a wide range of C-electrophiles, including alky...

Descripción completa

Detalles Bibliográficos
Autores principales: Deeming, Alex S., Russell, Claire J., Hennessy, Alan J., Willis, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883144/
https://www.ncbi.nlm.nih.gov/pubmed/24308313
http://dx.doi.org/10.1021/ol403122a
_version_ 1782298407417675776
author Deeming, Alex S.
Russell, Claire J.
Hennessy, Alan J.
Willis, Michael C.
author_facet Deeming, Alex S.
Russell, Claire J.
Hennessy, Alan J.
Willis, Michael C.
author_sort Deeming, Alex S.
collection PubMed
description [Image: see text] The addition of Grignard reagents or organolithium reagents to the SO(2)-surrogate DABSO generates a diverse set of metal sulfinates, suitable for direct conversion to sulfone products. The metal sulfinates can be trapped in situ with a wide range of C-electrophiles, including alkyl, allyl, and benzyl halides, epoxides, and (hetero)aryliodoniums.
format Online
Article
Text
id pubmed-3883144
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-38831442014-01-08 DABSO-Based, Three-Component, One-Pot Sulfone Synthesis Deeming, Alex S. Russell, Claire J. Hennessy, Alan J. Willis, Michael C. Org Lett [Image: see text] The addition of Grignard reagents or organolithium reagents to the SO(2)-surrogate DABSO generates a diverse set of metal sulfinates, suitable for direct conversion to sulfone products. The metal sulfinates can be trapped in situ with a wide range of C-electrophiles, including alkyl, allyl, and benzyl halides, epoxides, and (hetero)aryliodoniums. American Chemical Society 2013-12-05 2014-01-03 /pmc/articles/PMC3883144/ /pubmed/24308313 http://dx.doi.org/10.1021/ol403122a Text en Copyright © 2013 American Chemical Society Terms of Use CC-BY (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html)
spellingShingle Deeming, Alex S.
Russell, Claire J.
Hennessy, Alan J.
Willis, Michael C.
DABSO-Based, Three-Component, One-Pot Sulfone Synthesis
title DABSO-Based, Three-Component, One-Pot Sulfone Synthesis
title_full DABSO-Based, Three-Component, One-Pot Sulfone Synthesis
title_fullStr DABSO-Based, Three-Component, One-Pot Sulfone Synthesis
title_full_unstemmed DABSO-Based, Three-Component, One-Pot Sulfone Synthesis
title_short DABSO-Based, Three-Component, One-Pot Sulfone Synthesis
title_sort dabso-based, three-component, one-pot sulfone synthesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883144/
https://www.ncbi.nlm.nih.gov/pubmed/24308313
http://dx.doi.org/10.1021/ol403122a
work_keys_str_mv AT deemingalexs dabsobasedthreecomponentonepotsulfonesynthesis
AT russellclairej dabsobasedthreecomponentonepotsulfonesynthesis
AT hennessyalanj dabsobasedthreecomponentonepotsulfonesynthesis
AT willismichaelc dabsobasedthreecomponentonepotsulfonesynthesis

Ejemplares similares