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Coordinated conformational and compositional dynamics drive ribosome translocation
During translation elongation, the compositional factors, elongation factor G (EF-G; encoded by fusA) and transfer RNA (tRNA), alternately bind to the ribosome to direct protein synthesis, in turn regulating the conformation of the ribosome. Here, we use single-molecule fluorescence with zero-mode w...
Autores principales: | Chen, Jin, Petrov, Alexey, Tsai, Albert, O’Leary, Seán E., Puglisi, Joseph D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883222/ https://www.ncbi.nlm.nih.gov/pubmed/23624862 http://dx.doi.org/10.1038/nsmb.2567 |
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