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Unusual solitary neurofibroma on the lower lip of a child
Neurofibromas (NF) are benign tumors with involvement of the peripheral nerve, which is not frequently located in the oral cavity, and especially, extraordinary rarity on lower lip of a child. This report describes a case of a NF on lower lip in a 12-year-old Brazilian child. NF consists of a wide v...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883334/ https://www.ncbi.nlm.nih.gov/pubmed/24403799 http://dx.doi.org/10.4103/0976-237X.123061 |
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author | Borges, Alvaro Henrique Correia, Ramon De Medonça Borba, Alexandre Meirelles Guedes, Orlando Aguirre Estrela, Cynthia Rodrigues De Araújo Bandeca, Matheus Coelho |
author_facet | Borges, Alvaro Henrique Correia, Ramon De Medonça Borba, Alexandre Meirelles Guedes, Orlando Aguirre Estrela, Cynthia Rodrigues De Araújo Bandeca, Matheus Coelho |
author_sort | Borges, Alvaro Henrique |
collection | PubMed |
description | Neurofibromas (NF) are benign tumors with involvement of the peripheral nerve, which is not frequently located in the oral cavity, and especially, extraordinary rarity on lower lip of a child. This report describes a case of a NF on lower lip in a 12-year-old Brazilian child. NF consists of a wide variety of cell types, including Schwann cells, perineurial cells, and fibroblasts. Due to cellular heterogeneity, several hypotheses have been proposed to explain the histogenesis of this lesion. One of them, it support an origin of Schwannian, while others emphasize the participation of both Schwann cells and perineural cells. Excisional biopsy was performed to establish definitive diagnosis. Microscopically, the lesion was composed of interlacing bundles of elongated cells with wavy nuclei and small nerve fibers. Immunohistopathologic assessment showed cells positive for S-100, confirming the diagnosis of NF. No recurrence was observed after 1-year follow-up. Pediatric dentists must have a thorough knowledge of this unusual lesion. |
format | Online Article Text |
id | pubmed-3883334 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-38833342014-01-08 Unusual solitary neurofibroma on the lower lip of a child Borges, Alvaro Henrique Correia, Ramon De Medonça Borba, Alexandre Meirelles Guedes, Orlando Aguirre Estrela, Cynthia Rodrigues De Araújo Bandeca, Matheus Coelho Contemp Clin Dent Case Report Neurofibromas (NF) are benign tumors with involvement of the peripheral nerve, which is not frequently located in the oral cavity, and especially, extraordinary rarity on lower lip of a child. This report describes a case of a NF on lower lip in a 12-year-old Brazilian child. NF consists of a wide variety of cell types, including Schwann cells, perineurial cells, and fibroblasts. Due to cellular heterogeneity, several hypotheses have been proposed to explain the histogenesis of this lesion. One of them, it support an origin of Schwannian, while others emphasize the participation of both Schwann cells and perineural cells. Excisional biopsy was performed to establish definitive diagnosis. Microscopically, the lesion was composed of interlacing bundles of elongated cells with wavy nuclei and small nerve fibers. Immunohistopathologic assessment showed cells positive for S-100, confirming the diagnosis of NF. No recurrence was observed after 1-year follow-up. Pediatric dentists must have a thorough knowledge of this unusual lesion. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3883334/ /pubmed/24403799 http://dx.doi.org/10.4103/0976-237X.123061 Text en Copyright: © Contemporary Clinical Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Borges, Alvaro Henrique Correia, Ramon De Medonça Borba, Alexandre Meirelles Guedes, Orlando Aguirre Estrela, Cynthia Rodrigues De Araújo Bandeca, Matheus Coelho Unusual solitary neurofibroma on the lower lip of a child |
title | Unusual solitary neurofibroma on the lower lip of a child |
title_full | Unusual solitary neurofibroma on the lower lip of a child |
title_fullStr | Unusual solitary neurofibroma on the lower lip of a child |
title_full_unstemmed | Unusual solitary neurofibroma on the lower lip of a child |
title_short | Unusual solitary neurofibroma on the lower lip of a child |
title_sort | unusual solitary neurofibroma on the lower lip of a child |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883334/ https://www.ncbi.nlm.nih.gov/pubmed/24403799 http://dx.doi.org/10.4103/0976-237X.123061 |
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