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Unusual solitary neurofibroma on the lower lip of a child

Neurofibromas (NF) are benign tumors with involvement of the peripheral nerve, which is not frequently located in the oral cavity, and especially, extraordinary rarity on lower lip of a child. This report describes a case of a NF on lower lip in a 12-year-old Brazilian child. NF consists of a wide v...

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Autores principales: Borges, Alvaro Henrique, Correia, Ramon De Medonça, Borba, Alexandre Meirelles, Guedes, Orlando Aguirre, Estrela, Cynthia Rodrigues De Araújo, Bandeca, Matheus Coelho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883334/
https://www.ncbi.nlm.nih.gov/pubmed/24403799
http://dx.doi.org/10.4103/0976-237X.123061
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author Borges, Alvaro Henrique
Correia, Ramon De Medonça
Borba, Alexandre Meirelles
Guedes, Orlando Aguirre
Estrela, Cynthia Rodrigues De Araújo
Bandeca, Matheus Coelho
author_facet Borges, Alvaro Henrique
Correia, Ramon De Medonça
Borba, Alexandre Meirelles
Guedes, Orlando Aguirre
Estrela, Cynthia Rodrigues De Araújo
Bandeca, Matheus Coelho
author_sort Borges, Alvaro Henrique
collection PubMed
description Neurofibromas (NF) are benign tumors with involvement of the peripheral nerve, which is not frequently located in the oral cavity, and especially, extraordinary rarity on lower lip of a child. This report describes a case of a NF on lower lip in a 12-year-old Brazilian child. NF consists of a wide variety of cell types, including Schwann cells, perineurial cells, and fibroblasts. Due to cellular heterogeneity, several hypotheses have been proposed to explain the histogenesis of this lesion. One of them, it support an origin of Schwannian, while others emphasize the participation of both Schwann cells and perineural cells. Excisional biopsy was performed to establish definitive diagnosis. Microscopically, the lesion was composed of interlacing bundles of elongated cells with wavy nuclei and small nerve fibers. Immunohistopathologic assessment showed cells positive for S-100, confirming the diagnosis of NF. No recurrence was observed after 1-year follow-up. Pediatric dentists must have a thorough knowledge of this unusual lesion.
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spelling pubmed-38833342014-01-08 Unusual solitary neurofibroma on the lower lip of a child Borges, Alvaro Henrique Correia, Ramon De Medonça Borba, Alexandre Meirelles Guedes, Orlando Aguirre Estrela, Cynthia Rodrigues De Araújo Bandeca, Matheus Coelho Contemp Clin Dent Case Report Neurofibromas (NF) are benign tumors with involvement of the peripheral nerve, which is not frequently located in the oral cavity, and especially, extraordinary rarity on lower lip of a child. This report describes a case of a NF on lower lip in a 12-year-old Brazilian child. NF consists of a wide variety of cell types, including Schwann cells, perineurial cells, and fibroblasts. Due to cellular heterogeneity, several hypotheses have been proposed to explain the histogenesis of this lesion. One of them, it support an origin of Schwannian, while others emphasize the participation of both Schwann cells and perineural cells. Excisional biopsy was performed to establish definitive diagnosis. Microscopically, the lesion was composed of interlacing bundles of elongated cells with wavy nuclei and small nerve fibers. Immunohistopathologic assessment showed cells positive for S-100, confirming the diagnosis of NF. No recurrence was observed after 1-year follow-up. Pediatric dentists must have a thorough knowledge of this unusual lesion. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3883334/ /pubmed/24403799 http://dx.doi.org/10.4103/0976-237X.123061 Text en Copyright: © Contemporary Clinical Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Borges, Alvaro Henrique
Correia, Ramon De Medonça
Borba, Alexandre Meirelles
Guedes, Orlando Aguirre
Estrela, Cynthia Rodrigues De Araújo
Bandeca, Matheus Coelho
Unusual solitary neurofibroma on the lower lip of a child
title Unusual solitary neurofibroma on the lower lip of a child
title_full Unusual solitary neurofibroma on the lower lip of a child
title_fullStr Unusual solitary neurofibroma on the lower lip of a child
title_full_unstemmed Unusual solitary neurofibroma on the lower lip of a child
title_short Unusual solitary neurofibroma on the lower lip of a child
title_sort unusual solitary neurofibroma on the lower lip of a child
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883334/
https://www.ncbi.nlm.nih.gov/pubmed/24403799
http://dx.doi.org/10.4103/0976-237X.123061
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