Epigenetic Reprogramming of the Type III Interferon Response Potentiates Antiviral Activity and Suppresses Tumor Growth

Type III interferon (IFN-λ) exhibits potent antiviral activity similar to IFN-α/β, but in contrast to the ubiquitous expression of the IFN-α/β receptor, the IFN-λ receptor is restricted to cells of epithelial origin. Despite the importance of IFN-λ in tissue-specific antiviral immunity, the molecula...

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Detalles Bibliográficos
Autores principales: Ding, Siyuan, Khoury-Hanold, William, Iwasaki, Akiko, Robek, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883642/
https://www.ncbi.nlm.nih.gov/pubmed/24409098
http://dx.doi.org/10.1371/journal.pbio.1001758

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