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Inhibition of HIF prolyl-4-hydroxylases by FG-4497 Reduces Brain Tissue Injury and Edema Formation during Ischemic Stroke

Ischemic stroke results in disruption of the blood-brain barrier (BBB), edema formation and neuronal cell loss. Some neuroprotective factors such as vascular endothelial growth factor (VEGF) favor edema formation, while others such as erythropoietin (Epo) can mitigate it. Both factors are controlled...

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Detalles Bibliográficos
Autores principales:	Reischl, Stefan, Li, Lexiao, Walkinshaw, Gail, Flippin, Lee A., Marti, Hugo H., Kunze, Reiner
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883663/ https://www.ncbi.nlm.nih.gov/pubmed/24409307 http://dx.doi.org/10.1371/journal.pone.0084767

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