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DUSP1 Is a Novel Target for Enhancing Pancreatic Cancer Cell Sensitivity to Gemcitabine

Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer with a poor prognosis that is characterized by excessive mitogenic pathway activation and marked chemoresistance to a broad spectrum of chemotherapeutic drugs. Dual specificity protein phosphatase 1 (DUSP1) is a key negative regulator of mit...

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Detalles Bibliográficos
Autores principales: Liu, Fang, Gore, A. Jesse, Wilson, Julie L., Korc, Murray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883684/
https://www.ncbi.nlm.nih.gov/pubmed/24409315
http://dx.doi.org/10.1371/journal.pone.0084982

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