Cargando…
Highly Infectious Prions Generated by a Single Round of Microplate-Based Protein Misfolding Cyclic Amplification
Measurements of the presence of prions in biological tissues or fluids rely more and more on cell-free assays. Although protein misfolding cyclic amplification (PMCA) has emerged as a valuable, sensitive tool, it is currently hampered by its lack of robustness and rapidity for high-throughput purpos...
Autores principales: | Moudjou, Mohammed, Sibille, Pierre, Fichet, Guillaume, Reine, Fabienne, Chapuis, Jérôme, Herzog, Laetitia, Jaumain, Emilie, Laferrière, Florent, Richard, Charles-Adrien, Laude, Hubert, Andréoletti, Olivier, Rezaei, Human, Béringue, Vincent |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884057/ https://www.ncbi.nlm.nih.gov/pubmed/24381300 http://dx.doi.org/10.1128/mBio.00829-13 |
Ejemplares similares
-
Quaternary Structure of Pathological Prion Protein as a Determining Factor of Strain-Specific Prion Replication Dynamics
por: Laferrière, Florent, et al.
Publicado: (2013) -
Glycoform-independent prion conversion by highly efficient, cell-based, protein misfolding cyclic amplification
por: Moudjou, Mohammed, et al.
Publicado: (2016) -
Emergence of two prion subtypes in ovine PrP transgenic mice infected with human MM2-cortical Creutzfeldt-Jakob disease prions
por: Chapuis, Jérôme, et al.
Publicado: (2016) -
Prion strain-dependent tropism is maintained between spleen and granuloma and relies on lymphofollicular structures
por: Al-Dybiat, Iman, et al.
Publicado: (2019) -
The Physical Relationship between Infectivity and Prion Protein Aggregates Is Strain-Dependent
por: Tixador, Philippe, et al.
Publicado: (2010)