Cargando…

Bone marrow-derived mononuclear cells do not exert acute neuroprotection after stroke in spontaneously hypertensive rats

Bone marrow-derived mononuclear cells (BM-MNCs) were shown to improve the outcome in animal stroke models and clinical pilot studies on BM-MNCs for stroke patients were already conducted. However, relevant aspects of pre-clinical evaluation, such as the use of animals with comorbidities and dose-res...

Descripción completa

Detalles Bibliográficos
Autores principales:	Minnerup, Jens, Wagner, Daniel-Christoph, Strecker, Jan-Kolja, Pösel, Claudia, Sevimli-Abdis, Sevgi, Schmidt, Antje, Schilling, Matthias, Boltze, Johannes, Diederich, Kai, Schäbitz, Wolf-Rüdiger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884213/ https://www.ncbi.nlm.nih.gov/pubmed/24409120 http://dx.doi.org/10.3389/fncel.2013.00288

Ejemplares similares

Granulocyte colony-stimulating factor (G-CSF) treatment in combination with transplantation of bone marrow cells is not superior to G-CSF treatment alone after cortical stroke in spontaneously hypertensive rats
por: Diederich, Kai, et al.
Publicado: (2014)

Intracarotid administration of human bone marrow mononuclear cells in rat photothrombotic ischemia
por: Minnerup, Jens, et al.
Publicado: (2010)

Photochemically induced ischemic stroke in rats
por: Schmidt, Antje, et al.
Publicado: (2012)

Granulocyte-colony stimulating factor for stroke treatment: mechanisms of action and efficacy in preclinical studies
por: Minnerup, Jens, et al.
Publicado: (2009)

Sodium-Dependent Vitamin C Transporter 2 (SVCT2) Expression and Activity in Brain Capillary Endothelial Cells after Transient Ischemia in Mice
por: Gess, Burkhard, et al.
Publicado: (2011)

Effects of Different Exercise Strategies and Intensities on Memory Performance and Neurogenesis
por: Diederich, Kai, et al.
Publicado: (2017)

Monocyte Chemoattractant Protein-1-Deficiency Impairs the Expression of IL-6, IL-1β and G-CSF after Transient Focal Ischemia in Mice
por: Strecker, Jan-Kolja, et al.
Publicado: (2011)

Analysis of early phase and subsequent phase III stroke studies of neuroprotectants: outcomes and predictors for success
por: Minnerup, Jens, et al.
Publicado: (2014)

Density Gradient Centrifugation Compromises Bone Marrow Mononuclear Cell Yield
por: Pösel, Claudia, et al.
Publicado: (2012)

Immune Cell Infiltration into the Brain After Ischemic Stroke in Humans Compared to Mice and Rats: a Systematic Review and Meta-Analysis
por: Beuker, Carolin, et al.
Publicado: (2021)

Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats: an animal model of early-stage cerebral small vessel disease
por: Kaiser, Daniel, et al.
Publicado: (2014)

EPO for stroke therapy - Is there a future for further clinical development?
por: Minnerup, Jens, et al.
Publicado: (2010)

Erythropoietin for stroke treatment: dead or alive?
por: Minnerup, Jens, et al.
Publicado: (2011)

Functional Improvement after Photothrombotic Stroke in Rats Is Associated with Different Patterns of Dendritic Plasticity after G-CSF Treatment and G-CSF Treatment Combined with Concomitant or Sequential Constraint-Induced Movement Therapy
por: Frauenknecht, Katrin, et al.
Publicado: (2016)

Impact of age on the efficacy of bone marrow mononuclear cell transplantation in experimental stroke
por: Wagner, Daniel-Christoph, et al.
Publicado: (2012)

Autologous bone marrow mononuclear cells as neuroprotective treatment of amyotrophic lateral sclerosis
por: Ruiz-López, Francisco José, et al.
Publicado: (2016)

Late Onset Postpartum Eclampsia: It is Really Never Too Late—A Case of Eclampsia 8 Weeks after Delivery
por: Minnerup, Jens, et al.
Publicado: (2009)

Forced arm use is superior to voluntary training for motor recovery and brain plasticity after cortical ischemia in rats
por: Schneider, Armin, et al.
Publicado: (2014)

Isolation and Flow Cytometric Analysis of Immune Cells from the Ischemic Mouse Brain
por: Pösel, Claudia, et al.
Publicado: (2016)

Histopathological Investigation of Different MCAO Modalities and Impact of Autologous Bone Marrow Mononuclear Cell Administration in an Ovine Stroke Model
por: Boltze, Johannes, et al.
Publicado: (2011)

Flow cytometric characterization of brain dendritic cell subsets after murine stroke
por: Pösel, Claudia, et al.
Publicado: (2014)

Semaphorin 6A Improves Functional Recovery in Conjunction with Motor Training after Cerebral Ischemia
por: Rogalewski, Andreas, et al.
Publicado: (2010)

Time to overcome the translational roadblock: Introducing a new open access stroke journal
por: Schäbitz, Wolf-Rüdiger, et al.
Publicado: (2009)

Embolic stroke of undetermined source: identification of patient subgroups for oral anticoagulation treatment
por: Greeve, Isabell, et al.
Publicado: (2021)

Stroke recovery enhancing therapies: lessons from recent clinical trials
por: Rogalewski, Andreas, et al.
Publicado: (2021)

Influence of Delivery Method on Neuroprotection by Bone Marrow Mononuclear Cell Therapy following Ventral Root Reimplantation with Fibrin Sealant
por: Barbizan, Roberta, et al.
Publicado: (2014)

Synergetic Effects of Granulocyte-Colony Stimulating Factor and Cognitive Training on Spatial Learning and Survival of Newborn Hippocampal Neurons
por: Diederich, Kai, et al.
Publicado: (2009)

Bone Marrow Mesenchymal Stem Cells' Secretome Exerts Neuroprotective Effects in a Parkinson's Disease Rat Model
por: Mendes-Pinheiro, Bárbara, et al.
Publicado: (2019)

Principles and requirements for stroke recovery science
por: Sommer, Clemens J, et al.
Publicado: (2020)

Dying blood mononuclear cell secretome exerts antimicrobial activity
por: Kasiri, Mohammad Mahdi, et al.
Publicado: (2016)

Neuropeptides Exert Neuroprotective Effects in Alzheimer's Disease
por: Chen, Xin-Yi, et al.
Publicado: (2019)

Mirtazapine exerts astrocyte-mediated dopaminergic neuroprotection
por: Kikuoka, Ryo, et al.
Publicado: (2020)

Neuroprotection for Stroke: Current Status and Future Perspectives
por: Minnerup, Jens, et al.
Publicado: (2012)

Sudden Coma from Acute Bilateral M1 Occlusion: Successful Treatment with Mechanical Thrombectomy
por: Dietrich, Uwe, et al.
Publicado: (2014)

Arterial Hypertension Aggravates Innate Immune Responses after Experimental Stroke
por: Möller, Karoline, et al.
Publicado: (2015)

Intravenous Bone Marrow Mononuclear Cells Transplantation in Aged Mice Increases Transcription of Glucose Transporter 1 and Na(+)/K(+)-ATPase at Hippocampus Followed by Restored Neurological Functions
por: Takeuchi, Yukiko, et al.
Publicado: (2020)

Methylprednisolone exerts neuroprotective effects by regulating autophagy and apoptosis
por: Gao, Wei, et al.
Publicado: (2016)

Bone marrow mononuclear cells and acute myocardial infarction
por: Arnous, Samer, et al.
Publicado: (2012)

Irisin Exerts Neuroprotective Effects on Cultured Neurons by Regulating Astrocytes
por: Wang, Kexin, et al.
Publicado: (2018)

Stem Cell-Engineered Nanovesicles Exert Proangiogenic and Neuroprotective Effects
por: Kim, Han Young, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_65l1qiqdb28q8ihgr8fmqt43di