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2-Aminobenzoic acid–4-[2-(pyridin-4-yl)ethyl]pyridine (2/1)
The asymmetric unit of the title co-crystal, C(12)H(12)N(2)·2C(7)H(7)NO(2), comprises a centrosymmetric 4-[2-(pyridin-4-yl)ethyl]pyridine molecule and a 2-aminobenzoic acid molecule in a general position. The acid has a small twist between the carboxylic acid residue and the ring [dihedral ang...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884291/ https://www.ncbi.nlm.nih.gov/pubmed/24454067 http://dx.doi.org/10.1107/S1600536813027128 |
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author | Arman, Hadi D. Tiekink, Edward R. T. |
author_facet | Arman, Hadi D. Tiekink, Edward R. T. |
author_sort | Arman, Hadi D. |
collection | PubMed |
description | The asymmetric unit of the title co-crystal, C(12)H(12)N(2)·2C(7)H(7)NO(2), comprises a centrosymmetric 4-[2-(pyridin-4-yl)ethyl]pyridine molecule and a 2-aminobenzoic acid molecule in a general position. The acid has a small twist between the carboxylic acid residue and the ring [dihedral angle = 7.13 (6)°] despite the presence of an intramolecular N—H⋯O(carbonyl) hydrogen bond. Three-molecule aggregates are formed via O—H⋯N(pyridyl) hydrogen bonds, and these are connected into supramolecular layers in the bc plane by N—H⋯O(carbonyl) hydrogen bonds and π–π interactions between pyridine and benzene rings [inter-centroid distance = 3.6332 (9) Å]. Layers are connected along the a axis by weak π–π interactions between benzene rings [3.9577 (10) Å]. |
format | Online Article Text |
id | pubmed-3884291 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-38842912014-01-17 2-Aminobenzoic acid–4-[2-(pyridin-4-yl)ethyl]pyridine (2/1) Arman, Hadi D. Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers The asymmetric unit of the title co-crystal, C(12)H(12)N(2)·2C(7)H(7)NO(2), comprises a centrosymmetric 4-[2-(pyridin-4-yl)ethyl]pyridine molecule and a 2-aminobenzoic acid molecule in a general position. The acid has a small twist between the carboxylic acid residue and the ring [dihedral angle = 7.13 (6)°] despite the presence of an intramolecular N—H⋯O(carbonyl) hydrogen bond. Three-molecule aggregates are formed via O—H⋯N(pyridyl) hydrogen bonds, and these are connected into supramolecular layers in the bc plane by N—H⋯O(carbonyl) hydrogen bonds and π–π interactions between pyridine and benzene rings [inter-centroid distance = 3.6332 (9) Å]. Layers are connected along the a axis by weak π–π interactions between benzene rings [3.9577 (10) Å]. International Union of Crystallography 2013-10-05 /pmc/articles/PMC3884291/ /pubmed/24454067 http://dx.doi.org/10.1107/S1600536813027128 Text en © Arman and Tiekink 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Arman, Hadi D. Tiekink, Edward R. T. 2-Aminobenzoic acid–4-[2-(pyridin-4-yl)ethyl]pyridine (2/1) |
title | 2-Aminobenzoic acid–4-[2-(pyridin-4-yl)ethyl]pyridine (2/1) |
title_full | 2-Aminobenzoic acid–4-[2-(pyridin-4-yl)ethyl]pyridine (2/1) |
title_fullStr | 2-Aminobenzoic acid–4-[2-(pyridin-4-yl)ethyl]pyridine (2/1) |
title_full_unstemmed | 2-Aminobenzoic acid–4-[2-(pyridin-4-yl)ethyl]pyridine (2/1) |
title_short | 2-Aminobenzoic acid–4-[2-(pyridin-4-yl)ethyl]pyridine (2/1) |
title_sort | 2-aminobenzoic acid–4-[2-(pyridin-4-yl)ethyl]pyridine (2/1) |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884291/ https://www.ncbi.nlm.nih.gov/pubmed/24454067 http://dx.doi.org/10.1107/S1600536813027128 |
work_keys_str_mv | AT armanhadid 2aminobenzoicacid42pyridin4ylethylpyridine21 AT tiekinkedwardrt 2aminobenzoicacid42pyridin4ylethylpyridine21 |