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4-Meth­oxy-N-(pyridin-4-ylmeth­yl)-3-(tri­fluoro­meth­yl)benzamide monohydrate

In the title compound, C(15)H(13)F(3)N(2)O(2)·H(2)O, the dihedral angle between the benzene and pyridine rings is 74.97 (1)°. The –CF(3) group attached to the benzene ring is syn to the C=O bond in the adjacent side chain. In the crystal, mol­ecules are linked to one another through the water mol­ec...

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Detalles Bibliográficos
Autores principales: Sreenivasa, S., Mohan, N. R., Kumar, Vijith, Palakshamurthy, B. S., Arunakumar, D. B., Suchetan, P. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884365/
https://www.ncbi.nlm.nih.gov/pubmed/24454141
http://dx.doi.org/10.1107/S1600536813029103
Descripción
Sumario:In the title compound, C(15)H(13)F(3)N(2)O(2)·H(2)O, the dihedral angle between the benzene and pyridine rings is 74.97 (1)°. The –CF(3) group attached to the benzene ring is syn to the C=O bond in the adjacent side chain. In the crystal, mol­ecules are linked to one another through the water mol­ecules by strong N—H⋯O, O—H⋯O and O—H⋯N hydrogen bonds, forming a ladder-type network. The benzamide mol­ecules are also linked to one another through C—H⋯F inter­actions, forming C(6) chains parallel to the b-axis direction. Aromatic π–π stacking inter­actions [centroid–centroid separations = 3.7150 (1) and 3.7857 (1) Å] between adjacent pairs of pyridine and benzene rings are also observed, resulting in a three-dimensional architecture are also observed.