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4-Cyclopropyl-1-(6′-deoxy-1′,2′-O-isopropylidene-α-d-glucofuranosyl)-1H-1,2,3-triazole
In the title compound, C(14)H(21)N(3)O(5), the tetrahydrofuran ring adopts an envelope conformation with the C atom bearing the substituent as the flap. The pentafuranose ring adopts a twisted conformation about the C—C bond fusing the rings. The dihedral angle between these rings (all atoms), w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884407/ https://www.ncbi.nlm.nih.gov/pubmed/24427028 http://dx.doi.org/10.1107/S1600536813021351 |
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author | Zhang, Qiurong He, Peng Zhou, Guangqiang Yu, Kang Liu, Hongmin |
author_facet | Zhang, Qiurong He, Peng Zhou, Guangqiang Yu, Kang Liu, Hongmin |
author_sort | Zhang, Qiurong |
collection | PubMed |
description | In the title compound, C(14)H(21)N(3)O(5), the tetrahydrofuran ring adopts an envelope conformation with the C atom bearing the substituent as the flap. The pentafuranose ring adopts a twisted conformation about the C—C bond fusing the rings. The dihedral angle between these rings (all atoms), which are cis fused, is 72.89 (14)°. The cyclopropane ring is disordered over two orientations in a 0.576 (5):0.424 (5) ratio; the dihedral angles subtended to the triazole ring are 53.3 (11) and 46.6 (9)°, respectively. In the crystal, the molecules are linked by O—H⋯N and O—H⋯O hydrogen bonds, generating (001) sheets. A weak C—H⋯O interaction also occurs. |
format | Online Article Text |
id | pubmed-3884407 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-38844072014-01-14 4-Cyclopropyl-1-(6′-deoxy-1′,2′-O-isopropylidene-α-d-glucofuranosyl)-1H-1,2,3-triazole Zhang, Qiurong He, Peng Zhou, Guangqiang Yu, Kang Liu, Hongmin Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(14)H(21)N(3)O(5), the tetrahydrofuran ring adopts an envelope conformation with the C atom bearing the substituent as the flap. The pentafuranose ring adopts a twisted conformation about the C—C bond fusing the rings. The dihedral angle between these rings (all atoms), which are cis fused, is 72.89 (14)°. The cyclopropane ring is disordered over two orientations in a 0.576 (5):0.424 (5) ratio; the dihedral angles subtended to the triazole ring are 53.3 (11) and 46.6 (9)°, respectively. In the crystal, the molecules are linked by O—H⋯N and O—H⋯O hydrogen bonds, generating (001) sheets. A weak C—H⋯O interaction also occurs. International Union of Crystallography 2013-08-07 /pmc/articles/PMC3884407/ /pubmed/24427028 http://dx.doi.org/10.1107/S1600536813021351 Text en © Zhang et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Zhang, Qiurong He, Peng Zhou, Guangqiang Yu, Kang Liu, Hongmin 4-Cyclopropyl-1-(6′-deoxy-1′,2′-O-isopropylidene-α-d-glucofuranosyl)-1H-1,2,3-triazole |
title | 4-Cyclopropyl-1-(6′-deoxy-1′,2′-O-isopropylidene-α-d-glucofuranosyl)-1H-1,2,3-triazole |
title_full | 4-Cyclopropyl-1-(6′-deoxy-1′,2′-O-isopropylidene-α-d-glucofuranosyl)-1H-1,2,3-triazole |
title_fullStr | 4-Cyclopropyl-1-(6′-deoxy-1′,2′-O-isopropylidene-α-d-glucofuranosyl)-1H-1,2,3-triazole |
title_full_unstemmed | 4-Cyclopropyl-1-(6′-deoxy-1′,2′-O-isopropylidene-α-d-glucofuranosyl)-1H-1,2,3-triazole |
title_short | 4-Cyclopropyl-1-(6′-deoxy-1′,2′-O-isopropylidene-α-d-glucofuranosyl)-1H-1,2,3-triazole |
title_sort | 4-cyclopropyl-1-(6′-deoxy-1′,2′-o-isopropylidene-α-d-glucofuranosyl)-1h-1,2,3-triazole |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884407/ https://www.ncbi.nlm.nih.gov/pubmed/24427028 http://dx.doi.org/10.1107/S1600536813021351 |
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