Genome-wide identification of mRNAs associated with the protein SMN whose depletion decreases their axonal localization

Spinal muscular atrophy is a neuromuscular disease resulting from mutations in the SMN1 gene, which encodes the survival motor neuron (SMN) protein. SMN is part of a large complex that is essential for the biogenesis of spliceosomal small nuclear RNPs. SMN also colocalizes with mRNAs in granules tha...

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Detalles Bibliográficos
Autores principales: Rage, Florence, Boulisfane, Nawal, Rihan, Khalil, Neel, Henry, Gostan, Thierry, Bertrand, Edouard, Bordonné, Rémy, Soret, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884661/
https://www.ncbi.nlm.nih.gov/pubmed/24152552
http://dx.doi.org/10.1261/rna.040204.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884661/
https://www.ncbi.nlm.nih.gov/pubmed/24152552
http://dx.doi.org/10.1261/rna.040204.113

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