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Genome-wide identification of mRNAs associated with the protein SMN whose depletion decreases their axonal localization
Spinal muscular atrophy is a neuromuscular disease resulting from mutations in the SMN1 gene, which encodes the survival motor neuron (SMN) protein. SMN is part of a large complex that is essential for the biogenesis of spliceosomal small nuclear RNPs. SMN also colocalizes with mRNAs in granules tha...
Autores principales: | Rage, Florence, Boulisfane, Nawal, Rihan, Khalil, Neel, Henry, Gostan, Thierry, Bertrand, Edouard, Bordonné, Rémy, Soret, Johann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884661/ https://www.ncbi.nlm.nih.gov/pubmed/24152552 http://dx.doi.org/10.1261/rna.040204.113 |
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