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Hydroa Vacciniforme-Like Cutaneous T-cell Lymphoma
A 14-year-old Chinese girl had a 6-year history of recurrent lesions on her head, face, and limbs. Epstein-Barr virus (EBV)-IgM was positive. Histopathological findings revealed focal lymphocyte invasion in subcutaneous panniculus adiposus, mainly surrounding the blood vessels. Immunohistochemistry...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884939/ https://www.ncbi.nlm.nih.gov/pubmed/24470671 http://dx.doi.org/10.4103/0019-5154.123516 |
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author | Shi, Jian-Qiang Chen, Qiu-Xia Li, Shun-Fan Li, Wen |
author_facet | Shi, Jian-Qiang Chen, Qiu-Xia Li, Shun-Fan Li, Wen |
author_sort | Shi, Jian-Qiang |
collection | PubMed |
description | A 14-year-old Chinese girl had a 6-year history of recurrent lesions on her head, face, and limbs. Epstein-Barr virus (EBV)-IgM was positive. Histopathological findings revealed focal lymphocyte invasion in subcutaneous panniculus adiposus, mainly surrounding the blood vessels. Immunohistochemistry showed CD3+, CD4+, CD5+, CD8+, TIA-1+, GrB+, CD56-, and L26-. In situ hybridization staining for EBV-encoded small nonpolyadenylated RNA (EBER)-1 was positive. The patient showed significant improvement in clinical symptoms after being treated with acyclovir and IFN-α in this patient. |
format | Online Article Text |
id | pubmed-3884939 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-38849392014-01-27 Hydroa Vacciniforme-Like Cutaneous T-cell Lymphoma Shi, Jian-Qiang Chen, Qiu-Xia Li, Shun-Fan Li, Wen Indian J Dermatol Case Report A 14-year-old Chinese girl had a 6-year history of recurrent lesions on her head, face, and limbs. Epstein-Barr virus (EBV)-IgM was positive. Histopathological findings revealed focal lymphocyte invasion in subcutaneous panniculus adiposus, mainly surrounding the blood vessels. Immunohistochemistry showed CD3+, CD4+, CD5+, CD8+, TIA-1+, GrB+, CD56-, and L26-. In situ hybridization staining for EBV-encoded small nonpolyadenylated RNA (EBER)-1 was positive. The patient showed significant improvement in clinical symptoms after being treated with acyclovir and IFN-α in this patient. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3884939/ /pubmed/24470671 http://dx.doi.org/10.4103/0019-5154.123516 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Shi, Jian-Qiang Chen, Qiu-Xia Li, Shun-Fan Li, Wen Hydroa Vacciniforme-Like Cutaneous T-cell Lymphoma |
title | Hydroa Vacciniforme-Like Cutaneous T-cell Lymphoma |
title_full | Hydroa Vacciniforme-Like Cutaneous T-cell Lymphoma |
title_fullStr | Hydroa Vacciniforme-Like Cutaneous T-cell Lymphoma |
title_full_unstemmed | Hydroa Vacciniforme-Like Cutaneous T-cell Lymphoma |
title_short | Hydroa Vacciniforme-Like Cutaneous T-cell Lymphoma |
title_sort | hydroa vacciniforme-like cutaneous t-cell lymphoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884939/ https://www.ncbi.nlm.nih.gov/pubmed/24470671 http://dx.doi.org/10.4103/0019-5154.123516 |
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