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2-Amino-6-(piperidin-1-yl)-4-p-tolylpyridine-3,5-dicarbonitrile
In the title compound, C(19)H(19)N(5), the piperidine ring adopts a chair conformation. The pyridine ring is essentially planar, with a maximum deviation of 0.039 (2) Å for a C atom substituted with a carbonitrile group. The mean plane of the central pyridine ring makes the dihedral angles of 37.90 ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885062/ https://www.ncbi.nlm.nih.gov/pubmed/24454238 http://dx.doi.org/10.1107/S1600536813030845 |
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author | Inglebert, S. Antony Kamalraja, Jayabal Sethusankar, K. Vasuki, Gnanasambandam |
author_facet | Inglebert, S. Antony Kamalraja, Jayabal Sethusankar, K. Vasuki, Gnanasambandam |
author_sort | Inglebert, S. Antony |
collection | PubMed |
description | In the title compound, C(19)H(19)N(5), the piperidine ring adopts a chair conformation. The pyridine ring is essentially planar, with a maximum deviation of 0.039 (2) Å for a C atom substituted with a carbonitrile group. The mean plane of the central pyridine ring makes the dihedral angles of 37.90 (14) and 56.10 (12)° with the piperidine and benzene rings, respectively. In the crystal, molecules are linked via N—H⋯N and C—H⋯N hydrogen bonds, forming chains along [101], and enclosing R (2) (2)(17) ring motifs. The chains are linked by further C—H⋯N hydrogen bonds, forming two-dimensional networks lying parallel to (10-1), and enclosing inversion dimers with R (2) (2)(20) ring motifs. |
format | Online Article Text |
id | pubmed-3885062 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-38850622014-01-17 2-Amino-6-(piperidin-1-yl)-4-p-tolylpyridine-3,5-dicarbonitrile Inglebert, S. Antony Kamalraja, Jayabal Sethusankar, K. Vasuki, Gnanasambandam Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(19)H(19)N(5), the piperidine ring adopts a chair conformation. The pyridine ring is essentially planar, with a maximum deviation of 0.039 (2) Å for a C atom substituted with a carbonitrile group. The mean plane of the central pyridine ring makes the dihedral angles of 37.90 (14) and 56.10 (12)° with the piperidine and benzene rings, respectively. In the crystal, molecules are linked via N—H⋯N and C—H⋯N hydrogen bonds, forming chains along [101], and enclosing R (2) (2)(17) ring motifs. The chains are linked by further C—H⋯N hydrogen bonds, forming two-dimensional networks lying parallel to (10-1), and enclosing inversion dimers with R (2) (2)(20) ring motifs. International Union of Crystallography 2013-11-23 /pmc/articles/PMC3885062/ /pubmed/24454238 http://dx.doi.org/10.1107/S1600536813030845 Text en © Inglebert et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Inglebert, S. Antony Kamalraja, Jayabal Sethusankar, K. Vasuki, Gnanasambandam 2-Amino-6-(piperidin-1-yl)-4-p-tolylpyridine-3,5-dicarbonitrile |
title | 2-Amino-6-(piperidin-1-yl)-4-p-tolylpyridine-3,5-dicarbonitrile |
title_full | 2-Amino-6-(piperidin-1-yl)-4-p-tolylpyridine-3,5-dicarbonitrile |
title_fullStr | 2-Amino-6-(piperidin-1-yl)-4-p-tolylpyridine-3,5-dicarbonitrile |
title_full_unstemmed | 2-Amino-6-(piperidin-1-yl)-4-p-tolylpyridine-3,5-dicarbonitrile |
title_short | 2-Amino-6-(piperidin-1-yl)-4-p-tolylpyridine-3,5-dicarbonitrile |
title_sort | 2-amino-6-(piperidin-1-yl)-4-p-tolylpyridine-3,5-dicarbonitrile |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885062/ https://www.ncbi.nlm.nih.gov/pubmed/24454238 http://dx.doi.org/10.1107/S1600536813030845 |
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