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2-Amino-6-(piperidin-1-yl)-4-p-tolyl­pyridine-3,5-dicarbo­nitrile

In the title compound, C(19)H(19)N(5), the piperidine ring adopts a chair conformation. The pyridine ring is essentially planar, with a maximum deviation of 0.039 (2) Å for a C atom substituted with a carbonitrile group. The mean plane of the central pyridine ring makes the dihedral angles of 37.90 ...

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Autores principales: Inglebert, S. Antony, Kamalraja, Jayabal, Sethusankar, K., Vasuki, Gnanasambandam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885062/
https://www.ncbi.nlm.nih.gov/pubmed/24454238
http://dx.doi.org/10.1107/S1600536813030845
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author Inglebert, S. Antony
Kamalraja, Jayabal
Sethusankar, K.
Vasuki, Gnanasambandam
author_facet Inglebert, S. Antony
Kamalraja, Jayabal
Sethusankar, K.
Vasuki, Gnanasambandam
author_sort Inglebert, S. Antony
collection PubMed
description In the title compound, C(19)H(19)N(5), the piperidine ring adopts a chair conformation. The pyridine ring is essentially planar, with a maximum deviation of 0.039 (2) Å for a C atom substituted with a carbonitrile group. The mean plane of the central pyridine ring makes the dihedral angles of 37.90 (14) and 56.10 (12)° with the piperidine and benzene rings, respectively. In the crystal, mol­ecules are linked via N—H⋯N and C—H⋯N hydrogen bonds, forming chains along [101], and enclosing R (2) (2)(17) ring motifs. The chains are linked by further C—H⋯N hydrogen bonds, forming two-dimensional networks lying parallel to (10-1), and enclosing inversion dimers with R (2) (2)(20) ring motifs.
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spelling pubmed-38850622014-01-17 2-Amino-6-(piperidin-1-yl)-4-p-tolyl­pyridine-3,5-dicarbo­nitrile Inglebert, S. Antony Kamalraja, Jayabal Sethusankar, K. Vasuki, Gnanasambandam Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(19)H(19)N(5), the piperidine ring adopts a chair conformation. The pyridine ring is essentially planar, with a maximum deviation of 0.039 (2) Å for a C atom substituted with a carbonitrile group. The mean plane of the central pyridine ring makes the dihedral angles of 37.90 (14) and 56.10 (12)° with the piperidine and benzene rings, respectively. In the crystal, mol­ecules are linked via N—H⋯N and C—H⋯N hydrogen bonds, forming chains along [101], and enclosing R (2) (2)(17) ring motifs. The chains are linked by further C—H⋯N hydrogen bonds, forming two-dimensional networks lying parallel to (10-1), and enclosing inversion dimers with R (2) (2)(20) ring motifs. International Union of Crystallography 2013-11-23 /pmc/articles/PMC3885062/ /pubmed/24454238 http://dx.doi.org/10.1107/S1600536813030845 Text en © Inglebert et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Inglebert, S. Antony
Kamalraja, Jayabal
Sethusankar, K.
Vasuki, Gnanasambandam
2-Amino-6-(piperidin-1-yl)-4-p-tolyl­pyridine-3,5-dicarbo­nitrile
title 2-Amino-6-(piperidin-1-yl)-4-p-tolyl­pyridine-3,5-dicarbo­nitrile
title_full 2-Amino-6-(piperidin-1-yl)-4-p-tolyl­pyridine-3,5-dicarbo­nitrile
title_fullStr 2-Amino-6-(piperidin-1-yl)-4-p-tolyl­pyridine-3,5-dicarbo­nitrile
title_full_unstemmed 2-Amino-6-(piperidin-1-yl)-4-p-tolyl­pyridine-3,5-dicarbo­nitrile
title_short 2-Amino-6-(piperidin-1-yl)-4-p-tolyl­pyridine-3,5-dicarbo­nitrile
title_sort 2-amino-6-(piperidin-1-yl)-4-p-tolyl­pyridine-3,5-dicarbo­nitrile
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885062/
https://www.ncbi.nlm.nih.gov/pubmed/24454238
http://dx.doi.org/10.1107/S1600536813030845
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