2-Methyl­aspartic acid monohydrate

The title compound, C(5)H(9)NO(4)·H(2)O, is an isomer of the α-amino acid glutamic acid that crystallizes from water in its zwitterionic form as a monohydrate. It is not one of the 20 proteinogenic α-amino acids that are used in living systems and differs from the natural amino acids in that it has...

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Autores principales: Brewer, Greg, Burton, Aaron S., Dworkin, Jason P., Butcher, Ray J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885094/
https://www.ncbi.nlm.nih.gov/pubmed/24454270
http://dx.doi.org/10.1107/S1600536813032170
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author Brewer, Greg
Burton, Aaron S.
Dworkin, Jason P.
Butcher, Ray J.
author_facet Brewer, Greg
Burton, Aaron S.
Dworkin, Jason P.
Butcher, Ray J.
author_sort Brewer, Greg
collection PubMed
description The title compound, C(5)H(9)NO(4)·H(2)O, is an isomer of the α-amino acid glutamic acid that crystallizes from water in its zwitterionic form as a monohydrate. It is not one of the 20 proteinogenic α-amino acids that are used in living systems and differs from the natural amino acids in that it has an α-methyl group rather than an α-H atom. In the crystal, an O—H⋯O hydrogen bond is present between the acid and water mol­ecules while extensive N—H⋯O and O—H⋯O hydrogen bonds link the components into a three-dimensional array.
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spelling pubmed-38850942014-01-17 2-Methyl­aspartic acid monohydrate Brewer, Greg Burton, Aaron S. Dworkin, Jason P. Butcher, Ray J. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(5)H(9)NO(4)·H(2)O, is an isomer of the α-amino acid glutamic acid that crystallizes from water in its zwitterionic form as a monohydrate. It is not one of the 20 proteinogenic α-amino acids that are used in living systems and differs from the natural amino acids in that it has an α-methyl group rather than an α-H atom. In the crystal, an O—H⋯O hydrogen bond is present between the acid and water mol­ecules while extensive N—H⋯O and O—H⋯O hydrogen bonds link the components into a three-dimensional array. International Union of Crystallography 2013-11-30 /pmc/articles/PMC3885094/ /pubmed/24454270 http://dx.doi.org/10.1107/S1600536813032170 Text en © Brewer et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Brewer, Greg
Burton, Aaron S.
Dworkin, Jason P.
Butcher, Ray J.
2-Methyl­aspartic acid monohydrate
title 2-Methyl­aspartic acid monohydrate
title_full 2-Methyl­aspartic acid monohydrate
title_fullStr 2-Methyl­aspartic acid monohydrate
title_full_unstemmed 2-Methyl­aspartic acid monohydrate
title_short 2-Methyl­aspartic acid monohydrate
title_sort 2-methyl­aspartic acid monohydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885094/
https://www.ncbi.nlm.nih.gov/pubmed/24454270
http://dx.doi.org/10.1107/S1600536813032170
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