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Can the two mechanisms of tumor cell killing by radiation be exploited for therapeutic gain?
The radiation killing of tumor cells by ionizing radiation is best described by the linear–quadratic (LQ) model. Research into the underlying mechanisms of α- and β-inactivation has suggested that different molecular targets (DNA in different forms) and different microdosimetric energy deposits (spu...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885134/ https://www.ncbi.nlm.nih.gov/pubmed/24105710 http://dx.doi.org/10.1093/jrr/rrt111 |