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Nonviral Gene Delivery of Growth and Differentiation Factor 5 to Human Mesenchymal Stem Cells Injected into a 3D Bovine Intervertebral Disc Organ Culture System

Intervertebral disc (IVD) cell therapy with unconditioned 2D expanded mesenchymal stem cells (MSC) is a promising concept yet challenging to realize. Differentiation of MSCs by nonviral gene delivery of growth and differentiation factor 5 (GDF5) by electroporation mediated gene transfer could be an...

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Detalles Bibliográficos
Autores principales: Bucher, Christian, Gazdhar, Amiq, Benneker, Lorin M., Geiser, Thomas, Gantenbein-Ritter, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885261/
https://www.ncbi.nlm.nih.gov/pubmed/24454406
http://dx.doi.org/10.1155/2013/326828

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