Pharmacokinetics, Brain Delivery, and Efficacy in Brain Tumor-Bearing Mice of Glutathione Pegylated Liposomal Doxorubicin (2B3-101)

Brain cancer is a devastating disease affecting many people worldwide. Effective treatment with chemotherapeutics is limited due to the presence of the blood-brain barrier (BBB) that tightly regulates the diffusion of endogenous molecules but also xenobiotics. Glutathione pegylated liposomal doxorub...

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Detalles Bibliográficos
Autores principales: Gaillard, Pieter J., Appeldoorn, Chantal C. M., Dorland, Rick, van Kregten, Joan, Manca, Francesca, Vugts, Danielle J., Windhorst, Bert, van Dongen, Guus A. M. S., de Vries, Helga E., Maussang, David, van Tellingen, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885379/
https://www.ncbi.nlm.nih.gov/pubmed/24416140
http://dx.doi.org/10.1371/journal.pone.0082331

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