Strong Relationship between Oral Dose and Tenofovir Hair Levels in a Randomized Trial: Hair as a Potential Adherence Measure for Pre-Exposure Prophylaxis (PrEP)

BACKGROUND: Pre-exposure prophylaxis (PrEP) trials using tenofovir-based regimens have demonstrated that high levels of adherence are required to evaluate efficacy; the incorporation of objective biomarkers of adherence in trial design has been essential to interpretation, given the inaccuracy of se...

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Detalles Bibliográficos
Autores principales: Liu, Albert Y., Yang, Qiyun, Huang, Yong, Bacchetti, Peter, Anderson, Peter L., Jin, Chengshi, Goggin, Kathy, Stojanovski, Kristefer, Grant, Robert, Buchbinder, Susan P., Greenblatt, Ruth M., Gandhi, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885443/
https://www.ncbi.nlm.nih.gov/pubmed/24421901
http://dx.doi.org/10.1371/journal.pone.0083736

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