Randomised Controlled Trials May Underestimate Drug Effects: Balanced Placebo Trial Design

BACKGROUND: It is an inherent assumption in randomised controlled trials that the drug effect can be estimated by subtracting the response during placebo from the response during active drug treatment. OBJECTIVE: To test the assumption of additivity. The primary hypothesis was that the total treatme...

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Detalles Bibliográficos
Autores principales: Lund, Karen, Vase, Lene, Petersen, Gitte L., Jensen, Troels S., Finnerup, Nanna B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885519/
https://www.ncbi.nlm.nih.gov/pubmed/24416197
http://dx.doi.org/10.1371/journal.pone.0084104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885519/
https://www.ncbi.nlm.nih.gov/pubmed/24416197
http://dx.doi.org/10.1371/journal.pone.0084104

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