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Prediction of Detailed Enzyme Functions and Identification of Specificity Determining Residues by Random Forests

Determining enzyme functions is essential for a thorough understanding of cellular processes. Although many prediction methods have been developed, it remains a significant challenge to predict enzyme functions at the fourth-digit level of the Enzyme Commission numbers. Functional specificity of enz...

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Detalles Bibliográficos
Autores principales: Nagao, Chioko, Nagano, Nozomi, Mizuguchi, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885575/
https://www.ncbi.nlm.nih.gov/pubmed/24416252
http://dx.doi.org/10.1371/journal.pone.0084623